| |
| Prof
Paul Pui Hay BUT
Address: |
Room 286, Science Centre, CUHK (Off); |
| |
Room 234,
Hong Kong Institute of Biotechnology (Off); |
| |
Room E410,
Science Centre, CUHK (Lab) |
| Phone: |
(852)
2609-6299 (Room 286); |
| |
(852)
2609-6289 (Room 234); |
| |
(852)
2609-6289 (Lab) |
| Fax: |
(852)
2603-5646, (852) 2603-5745 |
| E-mail: |
paulbut@cuhk.edu.hk |
| Webpage: |
http://www.hkflora.com |
| Education |
| 1985 |
MBA, The
Chinese University of Hong Kong, Hong Kong |
| 1977 |
PhD (Botany),
University of California, Berkeley, USA |
| 1974 |
MA (Botany),
University of California, Berkeley, USA |
| 1972 |
BSc (Biology),
The Chinese University of Hong Kong, Hong Kong |
| Position |
| 1996-present |
Professor
II (Dept of Biology, The Chinese University of Hong Kong,
Hong Kong) |
| 1992-1999 |
Director
(Chinese Medicinal Material Research Centre, The Chinese University
of Hong Kong, Hong Kong) |
| Concurrent
Position |
| 2001-present |
Webmaster,
Hong Kong Flora and Vegetation <http://www.hkflora.com> |
| 2000-present |
Co-convenor
(Standardization and Safety Section, Institute of Chinese
Medicine, The Chinese University of Hong Kong, Hong Kong) |
| Professional
Activities |
Membership
in the Editorial Committee of the following Professional Organization:
Flora of China Project (Academia Sinica and Missouri Botanical
Garden) (1990-present) |
|
Research Interests |
| 1. |
Pharmacognosy
of traditional Chinese medicines |
| 2. |
Plant
systematics and chemotaxonomy |
| 3. |
Vegetation
and weed ecology |
|
Representative Publications |
| 1. |
He
Z.D., Lau K.M., But P.P.H., Dong
H., Ma S.C., Jiang R.W., Fung K.P., Ye W.C. and Sun H.D. (2003)
Antioxidative glycosides from the leaves of Ligustrum
robustum. Journal of Natural Products 66: 851-854. |
| 2. |
But
P.P.H.,
Cheng L., Chan P.K., Lau D.T.W., But J.W.H. (2002) Nostoc
flagelliforme and faked items retailed in Hong Kong.
Journal of Applied Phycology 14: 143-145. |
| 3. |
Jiang
R.W., But P.P.H., Ma S.C., Ye
W.C., Chan S.P., Mak T.C.W. (2002) Structure and antiviral
properties of macrocaesalmin, a novel cassane furanoditerpenoid
lactone from the seeds of Caesalpinia minax Hance.
Tetrahedron Letters 43: 2415-2418. |
| 4. |
Shaw
P.C., Wang J., and But P.P.H.
(Eds.) Authentication of Chinese Medicinal Materials by
DNA Technology. World Scientific, Singapore, 229 pp. |
| 5. |
Ma
S.C., Du J., But P.P.H., Deng
X.L., Zhang Y.W., Ooi V.E.C., Xu H.X., Lee S.H.S., Lee S.F.
(2002) Antiviral Chinese medicinal herbs against respiratory
syncytial virus. Journal of Ethnopharmacology 79:
205-211. |
| 6. |
Lau
D.T.W., Shaw P.C., Wang J., But P.P.H.
(2001) Authentication of medicinal Dendrobium species
by the internal transcribed spacer of ribosomal DNA. Planta
Medica 67: 456-460. |
| 7. |
Chan,
T.W.D., But, P.P.H., Cheng, S.W.,
Kwok, I.M.Y., Lau, F.W. and Xu, H.X. (2000) Differentiation
and authentication of Panax ginseng, Panax quinquefolius
and ginseng products by using HPLC/MS. Analytical Chemistry
72:1281-1287. |
| 8. |
Tomlinson,
B., Chan, T.Y.K., Chan, J.C.N., Critchley, J.A.J.H. and But,
P.P.H. (2000) Toxicity of complementary therapies:
an Eastern perspective. Journal of Clinical Pharmacology
40:451-456. |
| 9. |
Xie
Y.W., Ming D.S., Xu H.S., Dong H. and But
P.P.H. (2000) Vasorelaxing effects of Caesalpinia sappan:
involvement of endogenous nitric oxide. Life Sciences
67:1913-1918. |
| 10. |
Xu H.X., Wan M., Dong H., But P.P.H.
and Foo L.Y. (2000) Inhibitory activity of flavonoids and
tannins against HIV-1 protease. Biological & Pharmaceutical
Bulletin 23:1072-1076. |
| 11. |
Fung
A.Y.P., Look P.C.N., Chong L.Y.C., But
P.P.H. and Wong E. (1999) A controlled trial of traditional
Chinese herbal medicine in Chinese patients with recalcitrant
atopic dermatitis. International Journal of Dermatology
38:387-392. |
| 12. |
Lam
K.W. and But P.P.H. (1999) The
content of zeaxanthin in Gou Qi Zi, a potential health benefit
to improve visual acuity. Food Chemistry 67:173-176. |
| 13. |
Ngan
F.N., Shaw P.C., But P.P.H. and
Wang J. (1999) Molecular authentication of Panax
species. Phytochemistry 50:787-791. |
| 14. |
Song
J.Z., Xu H.X., Tian S.J. and But P.P.H.
(1999) Determination of quinolizidine alkaloids in traditional
Chinese herbal drugs by nonaqueous capillary electrophoresis.
Journal of Chromatography A 857:303-311. |
| 15. |
Lin
G, Zhou K.Y., Zhao X.G., Wang Z.T. and But
P.P.H. (1998) Determination of pyrrolizidine alkaloids
by on-line high performance liquid chromatography mass spectrometry
with an electrospray interface. Rapid Communications in
Mass Spectrometry 12:1445-1456. |
| Patents |
Wang
J, Shaw PC, But PPH and Ngai
KFN (1999-2001) Polymerase chain reaction fragment length
polymorphism test for the authentication of traditional Chinese
medicines. US Patents No 5,876,977 and 6,309,840. Also Chinese
Patent 98100001.0. (2003). |
| |
| Research
Grants |
Research
Grants Council (RGC) Earmarked Grants |
| 1999-2001 |
Novel
Anti-herpes Agent from Natural Product - HK$580,000 |
| |
| Hong
Kong Jockey Club Institute of Chinese Medicine |
| 2003-2006 |
Authentication
and Quality Assessment of Chinese Medicinal Materials by DNA
and Chemical Technologies (co-principal investigator) |
Industrial Support Fund |
| 2000-2003 |
Innovative
Development of Herbal Products for Women of All Ages - HK$9,200,000
(co-principal investigator) |
| 1999-2002 |
Development
of Potent Antiviral Chinese Medicines - HK$3,280,000 (co-principal
investigator) |
| 1998-2001 |
Development
of Chinese Medicines and Dietary Supplements for Treating
Gastrointestinal Disorders and Cough - HK$8,799,000 |
| 1997-2000 |
Chemical
Quality Control of Chinese Medicines for Export - HK$2,480,000 |
| 1995-1997 |
Laboratory
for Quality Control of Chinese Medicines and Health Foods
Based on Chemical Components - HK$7,103,000 |
| |
|
| Quality
Education Fund |
| 2003-2005 |
Multi-school
Collaboration in the Information Technology for Hong Kong
Flora and Vegetation - HK$1,938,000 |
| 2001-2003 |
A
Web-based Database and Training on Hong Kong Flora and Vegetation
- HK$1,500,000 |
|
|
|
