| Prof
Peter Chi Keung CHEUNG
Address: |
Room EG09, Science Centre, CUHK (Off); |
| |
Room 380,
Science Centre, CUHK (Lab) |
| Phone: |
(852)
3943-6144 (Off); |
| |
(852)
3943-6272 (Lab) |
| Fax: |
(852)
2603-5646, (852) 2603-5745 |
| E-mail: |
petercheung@cuhk.edu.hk |
| Education |
| 1987-1990 |
PhD
(Food Carbohydrate), The University of New South Wales, Australia |
| 1985-1986 |
MChem
(Food and Drug Chemistry), The University of New South Wales,
Australia |
| 1981-1983 |
BSc (Chemistry),
The University of Hong Kong, Hong Kong |
| Position |
| 1998-present
|
Associate
Professor (Dept of Biology, The Chinese University of Hong
Kong, Hong Kong) |
| 1994-1997 |
Assistant
Professor (Dept of Biology, The Chinese University of Hong
Kong, Hong Kong) |
| 1990-1993 |
Food Scientist
(Food Research Laboratory, Division of Food Science and Technology,
The Commonwealth Scientific and Industrial Research Organization) |
| |
|
| Concurrent
Position |
| 2005-present |
Director
(Food and Nutritional Sciences programme, The Chinese University
of Hong Kong, Hong Kong) |
| |
|
| Professional
Activities |
| Appointments in the following Professional Organization: |
| 1997-present |
Past Chairman, Vice-chairman and Adviser (the Hong Kong Food Science and Technology Association) |
| |
|
| Membership in the following Professional Organizations: |
| The Australian Institute of Food Science and Technology (AIFST) |
| Institute of Food Technologists (IFT) |
| American Chemical Society (ACS) |
| |
|
| Research
Interests |
| 1. Fungal (mushroom) and plant cell wall polysaccharides: structure and function |
| 2. Functional food and nutraceuticals: prebiotics and synbiotics |
| 3. Dietary fiber: chemical characterization and biological activities |
| |
|
| Representative
Publications For the Past Five Years |
| 1. |
Ma, Y.T. and Cheung, P.C.K. (2007). Spectrophotometric determination of phenolic compounds by enzymatic and chemical methods ¡V A comparison of structure-activity relationship. Journal of Agricultural and Food Chemistry 55, 4222-4228. |
| 2. |
Wong, S.M., Wong, K.K., Chiu, L.C.M. and Cheung, P.C.K. (2007). Non-starch polysaccharides from different developmental stages of Pleurotus tuber-regium inhibited the growth of human acute promyelocytic leukemia HL-60 cells by cell-cycle arrest and/or apoptotic induction. Carbohydrate Polymers 68, 206-217. |
| 3. |
Zhang, M., Cui, S.W.W., Cheung, P.C.K. and Wang, Q. (2007). Antitumor polysaccharides from mushrooms: A review on isolation process, structural characteristics and antitumor activity. Trends in Food Science and Technology 18, 4-19. |
| 4. |
Zhang, M., Cheung, P.C.K., Chiu, L.C.M., Wong, E.Y.L. and Ooi, V.E.C. (2006). Cell cycle arrest and apoptosis induction in human breast carcinoma MCF-7 by carboxymethylated )- ¡Vglucan from the mushroom sclerotia of Pleurotus tuber-regium. Carbohydrate Polymers 66, 455-462. |
| 5. |
Tao Y., Zhang, L. and Cheung, P.C.K. (2006). Physicochemical properties and antitumor activities of water-soluble native and sulfated hyperbranched mushroom polysaccharides. Carbohydrate Research 341, 2261-2269. |
| 6. |
Zhang, M., Chiu, L.C.M., Cheung, P.C.K. and Ooi, V.E.C. (2006). Growth-inhibitory effects of a s-glucan from the mycelium of Poria cocos on human breast carcinoma MCF-7 cells: Cell-cycle arrest and apoptosis induction. Oncology Reports 15, 637-643. |
| 7. |
Wong, K.H., Katsumata, S.-I., Masuyama, R., Uehara, M., Suzuki, K. and Cheung, P.C.K. (2006). Dietary fiber from mushroom sclerotia: 4. In vivo mineral absorption using ovariectomized rat model. Journal of Agricultural and Food Chemistry 54, 1921-1927. |
| 8. |
Wong, K.H., Wong, K.Y., Kwan, H.S. and Cheung, P.C.K. (2005). Dietary fiber from mushroom sclerotia: 3. In vitro fermentability using human faecal microflora. Journal of Agricultural and Food Chemistry 53, 9407-9412. |
| 9. |
Wong, K.H. and Cheung, P.C.K. (2005). Dietary fiber from mushroom sclerotia: 2. In vitro mineral binding capacity under sequential simulated physiological conditions of the human gastrointestinal tract. Journal of Agricultural and Food Chemistry 53, 9401-9406. |
| 10. |
Wong, K.H. and Cheung, P.C.K. (2005). Dietary fiber from mushroom sclerotia: 1. Preparation, physico-chemical and functional properties. Journal of Agricultural and Food Chemistry 53, 9539-9400. |
| 11. |
Lo, K.M. and Cheung, P.C.K. (2005). Antioxidant activities of extracts from the fruiting bodies of Agrocybe aegerita var. alba. Food Chemistry 89, 533-539. |
| 12. |
Cheung, L.M. and Cheung, P.C.K. (2005). Mushroom extracts with antioxidant activity against lipid oxidation. Food Chemistry 89, 403-409. |
| 13. |
Zhang, M., Cheung, P.C.K., Ooi, V.E.C. and Zhang, L. (2004). Evaluation of sulfated fungal £]-glucans from the sclerotium of Pleurotus tuber-regium as a potential water-soluble anti-viral agent. Carbohydrate Research 339, 2297-2301. |
| 14. |
Zhang, M., Cheung, P.C.K., Zhang, L., Chiu, C.M. and Ooi, V.E.C. (2004). Carboxymethylated £]-glucans from mushroom sclerotium of Pleurotus tuber-regium as novel water-soluble anti-tumor agent. Carbohydrate Polymers 57, 319-325. |
| 15. |
Zhang, M., Zhang, L., Cheung, P.C.K. and Ooi, V.E.C. (2004). Molecular weight and anti-tumor activity of the water-soluble polysaccharides isolated by hot water and ultrasonic treatment from the sclerotia and mycelia of Pleurotus tuber-regium. Carbohydrate Polymers 56, 123-128. |
| 16. |
Wu, J.Z., Cheung, P.C.K., Wong, K.H. and Huang, N.L. (2004). Studies on the submerged fermentation of Pleurotus tuber-regium (Fr.) Singer: 2. Effect of carbon-to-nitrogen ratio of the culture medium on the content and composition of the mycelial dietary fibre in mycelium. Food Chemistry 85, 101-105. |
| 17. |
Wong, K.H., Cheung, P.C.K. and Wu, J.Z. (2003). Biochemical and microstructural characteristics of insoluble and soluble dietary fiber prepared from mushroom sclerotia of Pleurotus tuber-regium, Polyporus rhinoceros and Wolfporia cocos. Journal of Agricultural and Food Chemistry 51, 7197-7202. |
| 18. |
Cheung, L.M., Cheung, P.C.K. and Ooi, V.E.C. (2003). Antioxidant activity and total phenolics of edible mushroom extracts. Food Chemistry 81, 249-255. |
| 19. |
Wu J.Z., Cheung, P.C.K., Wong, K.H. and Huang, N.L. (2003). Studies on the submerged fermentation of Pleurotus tuber-regium (Fr.) Singer: 1. Physical and chemical factors affecting the rate of mycelial growth and bioconversion efficiency. Food Chemistry 81, 389-393. |
| 20. |
Zhang, M., Zhang, L. and Cheung, P.C.K. (2003). Molecular mass and chain conformation of carboxymethylated derivatives of £]-glucan from sclerotia of Pleurotus tuber-regium. Biopolymers 68, 150-159. |
| |
|
| Research
Grants For the Past Five Years |
Research Grants Council (RGC) Competitive Earmarked Research Grants (CERG) |
| 2005-2007 |
Mushroom non-digestible carbohydrates as novel £]-glucan type prebiotics: Their preparation and in vitro microbial fermentation - HK$ 718,957 (principal investigator) |
| 2002-2004 |
A
Mechanistic Study of the Immunopotentiating and Antitumor
Effects of Native and Chemically Modified Nonstarch Polysaccharides
[(1¡÷3)-£]-D-Glucans]
from Mushroom Sclerotia - HK$1,036,000 (principal investigator) |
| |
In
Vitro and in Vivo Anticancer Studies of Novel Polyunsaturated
Fatty Acids (DHA, EPA) Purified and Characterized from Several
Enriched Microalgae - HK$876,000 (co-investigator) |
|