| Prof
Norman Ying Shiu WOO
(Chairman of the Department)
Address: |
Room
G78, Science Centre, CUHK (Off); |
| |
Room E401,
Science Centre, CUHK (Lab); |
| |
Rm 106,
Simon FS Li Marine Science Laboratory (MSL), CUHK (Lab) |
| Phone: |
(852)
2609-6148 (Room G85); |
| |
(852)
2609-6280 (Room E401); |
| |
(852)
2609-6770 (MSL) |
| Fax: |
(852)
2603-5646, (852) 2603-5745 |
| E-mail: |
normanwoo@cuhk.edu.hk |
| Education |
| 1976 |
PhD (Zoology),
University of Hong Kong, Hong Kong |
| 1973 |
BSc (Zoology),
University of Hong Kong, Hong Kong |
| Position |
| 2004-present |
Professor
and Chairman (Dept of Biology, The Chinese University of Hong
Kong, Hong Kong) |
| 1995-2004 |
Professor
(Dept of Biology, The Chinese University of Hong Kong, Hong
Kong)
|
| 1993-1995 |
Reader
(Dept of Biology, The Chinese University of Hong Kong, Hong
Kong)
|
| 1985-1992 |
Senior
Lecturer (Dept of Biology, The Chinese University of Hong
Kong, Hong Kong)
|
| 1977-1985 |
Lecturer
(Dept of Biology, The Chinese University of Hong Kong, Hong
Kong)
|
| 1976-1977 |
Research
Zoologist (Dept of Zoology, University of California, Berkeley,
USA)
|
| Professional
Activities |
| Appointments
in the following Professional Organizations: |
| Chairman
(Organizing Committee, Pacific Congress on Marine Science and
Technology (PACON 97) |
| Advisor,
Pacific Congress on Marine Science and Technology, Hawaii, USA |
| Advisor,
CK Technology International Inc, Hong Kong |
| Honorary
Advisor, Ocean Park Limited, Hong Kong |
| Assessor,
Environment and Food Bureau, Hong Kong SAR Government |
Editorial Referee of the following International Journals: |
| American
Journal of Physiology |
| Aquaculture |
| Archives
of Environmental Contamination and Toxicology |
| Asian
Marine Biology |
| Amino
Acids |
| Comparative
Biochemistry & Physiology |
| Environmental
Biology of Fishes |
| Environmental
Toxicology |
| Fish Physiology
and Biochemistry |
| General
& Comparative Endocrinology |
| Journal
of Experimental Zoology |
| Journal
of Fish Biology |
Membership in the following Professional
Organizations: |
| Asia and
Oceania Society for Comparative Endocrinology |
| Hong Kong
Institution of Science |
| Marine
Biological Association of Hong Kong |
| Society
for the Study of Endocrinology, Reproduction and Metabolism
(Hong Kong) |
| The Society
for Integrative and Comparative Biology (USA) |
| Research
Interests |
| 1. |
Fish endocrinology |
| 2. |
Piscine
osmoregulatory physiology |
| 3. |
Biology
of stress and heat shock proteins |
| 4. |
Vibriosis
|
| Representative
Publications |
| 1. |
Wong, M.K.S., Ge, W. and Woo, N.Y.S. (2007) Positive feedback of hepatic angiotensinogen expression in silver sea bream (Sparus sarba). Molecular and Cellular Endocrinology 263: 103-111. |
| 2. |
Deane, E.E., Zhou, L.R. and Woo, N.Y.S. (2006) Cortisol can be pro- or anti-apoptotic in sea bream cells: potential role of HSP70 induction for cytoprotection. Molecular and Cellular Endocrinology 259: 57-64. |
| 3. |
Deane, E.E. and Woo, N.Y.S. (2006) Impact of heavy metals and organochlorines on hsp70 and hsc70 gene expression in black sea bream fibroblasts. Aquatic Toxicology 79: 9-15. |
| 4. |
Deane, E.E. and Woo, N.Y.S. (2006) Molecular cloning of growth hormone from silver sea bream: effects of abiotic and biotic stress on transcriptional and translational expression. Biochemical and Biophysical Research Communications 342: 1077-1082.
|
| 5. |
Wong, M.K.S., Takei, Y. and Woo, N.Y.S. (2006) Differential status of the renin-angiotensin system in silver sea bream (Sparus sarba) in different salinities. General and Comparative Endocrinology 149: 81-89. |
| 6. |
Wong, M.K.S., and Woo, N.Y.S. (2006) Rapid changes in renal morphometrics in sea bream Sparus sarba on exposure to different salinities. Journal of Fish Biology 69: 770-782.
|
| 7. |
Deane, E.E. and Woo, N.Y.S. (2005) Cloning and characterization of the hsp70 multigene family from silver sea bream: modulated gene expression between warm and cold temperature acclimation. Biochemical and Biophysical Research Communications 330: 776-783. |
| 8. |
Deane, E.E. and Woo, N.Y.S. (2005) Cloning and characterization of sea bream Na-K-ATPase alpha and beta subunit genes: In vitro effects of hormones on transcriptional and translational expression. Biochemical and Biophysical Research Communications 331: 1229-1238. |
| 9. |
Deane, E.E. and Woo, N.Y.S. (2005) Expression studies on glucose-6-phosphate dehydrogenase in sea bream: Effects of growth hormone, somatostatin, salinity and temperature. Journal of Experimental Zoology 303A: 676-688. |
| 10. |
Deane, E.E. and Woo, N.Y.S. (2005) Evidence for disruption of Na+-K+-ATPase and hsp70 during vibriosis of sea bream, Sparus (=Rhabdosargus) sarba Forskkal. Journal of Fish Diseases 28: 239-251. |
| 11. |
Deane, E.E. and Woo, N.Y.S. (2005) Modulation of -actin, insulin-like growth factor I and glucose-6-phosphate dehydrogenease gene expression, during vibriosis of sea bream, Sparus (= Rhabdosargus) sarba Forsskal. Journal of Fish Diseases 28: 593-601. |
| 12. |
Deane, E.E. and Woo, N.Y.S. (2004) Differential gene expression associated with euryhalinity in sea bream (Sparus sarba). American Journal of Physiology Regulatory Integrative and Comparative Physiology 287: R1054-R1063. |
| 13. |
Deane, E.E., Li, J., and Woo, N.Y.S. (2004) Modulated heat shock protein expression during pathogenic stress of sea bream. Diseases of Aquatic Organisms 62: 205-215. |
| 14. |
Deane,
E.E. and Woo, N.Y.S. (2003)
Ontogeny of thyroid hormones, cortisol, hsp70 and hsp90 during
silver sea bream larval development. Life Sciences 72: 805-818. |
| 15. |
Deane,
E. E., Kelly, S. P., Collins, P. M. and Woo,
N.Y.S. (2003) Larval development of silver sea bream
(Sparus sarba): ontogeny of RNA-DNA ratio, GH, IGF-I
and Na+-K+-ATPase. Marine Biotechnology 5: 79-91. |
| 16. |
Li, J., Zhou, L.R., and Woo, N.Y.S. (2003) Invasion route and pathogenic mechanisms of Vibrio alginolyticus to silver sea bream Sparus sarba. Journal of Aquatic Animal Health 15: 302-313. |
| 17. |
Zhou, L.R., Deane, E.E. and Woo, N.Y.S. (2003) Development of a black sea bream fibroblast cell line and its potential use as an in vitro model for stress protein studies. Fish Physiology and Biochemistry 29: 255-262. |
| 18. |
Deane,
E.E., Kelly, S. P., Luk, J.C.Y. and Woo,
N.Y.S. (2002) Chronic salinity adaptation modulates
hepatic heat shock protein and insulin-like growth factor
I expression in black sea bream. Marine Biotechnology
4: 193-205. |
| 19. |
Deane,
E.E., Li, J. and Woo, N.Y.S.
(2001) Hormonal status and phagocytic activity in sea bream
infected with vibriosis. Comparative Biochemistry and
Physiology 129B: 687-693. |
| 20. |
Deane,
E.E., Kelly, S.P. and Woo, N.Y.S.
(2000) Hypercortisolemia does not affect the branchial osmoregulatory
responses of the marine teleost Sparus sarba. Life
Sciences 66:1435-1444. |
| 21. |
Kelly,
S.P., Larsen, S.D., Collins, P.M. and Woo,
N.Y.S. (2000) Quantitation of inert feed utilization
in larval silver sea bream (Sparus sarba) using auto-fluorescence
of alginate-based microparticulate diets. Fish Physiology
and Biochemistry 22:109-117. |
| 22. |
Deane,
E.E., Kelly, S.P., Chow, I.N.K. and Woo,
N.Y.S. (2000) Effect of a prolactin pharmacological
stimulant (sulpiride) and suppressant (bromocriptine) on heat
shock protein 70 expression in Sparus sarba. Fish
Physiology and Biochemistry, 22:125-133. |
| 23. |
Deane,
E.E., Kelly, S.P., Lo, C.K.M., and Woo,
N.Y.S. (1999) Effects of GH, prolactin and cortisol
on hepatic HSP70 expression in a marine teleost Sparus
sarba. Journal of Endocrinology 161:413-421. |
| 24. |
Kelly,
S.P. and Woo, N.Y.S. (1999) The
response of sea bream during hyposmotic exposure. Journal
of Fish Biology 55:732-750. |
| 25. |
Kelly,
S.P. and Woo, N.Y.S. (1999) Cellular
and biochemical characterization of hyposmotic adaptation
in a marine teleost, Sparus sarba. Zoological
Science 16:505-514. |
| 26. |
Kelly,
S.P., Chow, I.N.K. and Woo, N.Y.S.
(1999) Alterations in Na+-K+-ATPase activity and gill chloride
cell exposure of juvenile black seabream (Mylio macrocephalus)
in response to salinity and ration size. Aquaculture 172:351-367. |
| 27. |
Kelly,
S.P., Chow, I.N.K. and Woo, N.Y.S.
(1999) The haloplasticity of the black seabream (Mylio
macrocephalus): hypersaline to freshwater acclimation.
Journal of Experimental Zoology 283:226-241. |
| 28. |
Kelly,
S.P., Chow, I.N.K. and Woo, N.Y.S.
(1999) Effects of prolactin and growth hormone on strategies
of hyposmotic adaptation in a marine teleost, Sparus sarba.
General and Comparative Endocrinology 113:9-22. |
| 29. |
Li,
J., Ye, J., Foo, R.W.T., Ling, J.M.L., Xu, H.S. and Woo,
N.Y.S. (1999) Antibiotic resistance and plasmid profiles
of vibrio isolates from cultured silver sea bream, Sparus
sarba. Marine Pollution Bulletin, 39:245-249. |
| Research
Grants |
| Research
Grants Council (RGC) Earmarked Grants |
| 2005-2007 |
RGC Earmarked Grant: Molecular strategies of temperature acclimation in the sea bream |
| 2003-2006 |
Role
of aquaporin water channels in the osmoregulatory strategy
of the euryhaline marine teleost Sparus sarba |
| 2002-2005 |
Growth
hormone and insulin-like growth factor-I as anti-apoptotic
factors via modulated HSP70 expression in sea bream |
| 2001-2004 |
Stimulation
of glucose-6-phosphate dehydrogenase activity in sea bream:
metabolic significance and potential applications |
| 2000-2002 |
Modulation
of Gill Na+-K+-ATPase Expression by Salinity and Hormonal
Factors in the Sea Bream, Sparus sarba |
| 1999-2002 |
Protective
Effects of Heat Shock Protein 70 (HSP70) against Environmental
and Pathogenic Stress in the Marine Teleost Sparus sarba |
| 1998-2000 |
Enhancing
Immunological Competence of Silver Sea Bream (Sparus sarba)
through the Combined Application of Salinity Adaptation, Hormonal
Factors and Specific Vaccines |
| 1997-2000 |
Evaluation
of Novel Microencapsulated Formulations for the Improved Survival
and Development of Cultured Marine Fish Larvae |
Research Grant (Area of Excellence) |
| 2004-2009 |
Area of Excellence (AoE) Centre for Marine Environmental Research and Innovative Technology (MERIT) |
Contract Research |
| 2001-2002 |
Suitability
of Crescent Island and Kat O Area to be established as a marine
park - Agriculture, Fisheries and Conservation Department,
Hong Kong SAR Government (co-investigator) |
| 2000-2001 |
Assessment
of Environmental Safety of Aquaculture Farms using Biochemical
Indicators of Distress - Asian Pacific Economic Cooperation
Secretariat (APEC Secretariat) (co-investigator) |
| 1999-2000 |
Study
on the Suitability of Ping Chau to be Established as Marine
Park or Marine Reserve - Department of Agriculture and Fisheries,
Hong Kong SAR Government (co-investigator) |
Strategic
Grant |
| 1999-2003 |
Strategies
for the Improvement of Marine Fish and Shrimp Culture: a Molecular
Biological Approach |
Mainline Research Scheme |
| 1995-1997 |
Expression
of Heat Shock Proteins in Cultured Hepatocytes from the Sea
Bream: a Sensitive Biological Model for Detecting Environmental
Stress |
Research Grant, National Science
Foundation, China |
| 1999-2002 |
Studies
on Immunological Control of Vibriosis in Marine Fish Culture
(co-investigator) |
CUHK Seed Funding for the AoE Project |
| 2000-2001 |
Marine
Biotechnology |
Direct Grants of the Research Committee,
CUHK |
| 2003-2004 |
Validation of an in vitro system for assessing the effects
of mitogenic hormones on stress protein expression |
| 2000-2002 |
An investigation into the effects of growth hormone, prolactin
and cortisol on branchial HSP90, HSP70, and HSP60 expression
in silver sea bream |
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