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photo of Prof. Jiang XIA

Prof. Jiang XIA

Associate Professor

location Room 360 Science Centre
Phone No. (852) 3943 6165
Fax No. (852) 2603 5057
Email jiangxia@cuhk.edu.hk


1999 B.Sc. Nanjing University
2002 M.S. Nanjing University
2006 Ph.D. Stanford University


Since 2014
Associate Professor (by courtesy), 
School of Life Sciences, 
The Chinese University of Hong Kong
Since 2014
Associate Professor, 
Department of Chemistry, 
The Chinese University of Hong Kong
Assistant Professor, 
The Chinese University of Hong Kong
Research Associate, 
Howard Hughes Medical Institute
Postdoctoral scholar, 
California Institute of Technology

Research Interests

Protein chemistry, bioorganic chemistry and chemical biology

Representative Publications

  1. Yu, Y.; Liu, M.; Ng, T. T.; Huang, F.; Nie, Y.; Wang, R.; Yao, Z-P.; Li, Z.; Xia, J.* PDZ-reactive peptide activates ephrin-B reverse signaling and inhibits neuronal chemotaxis. ACS Chem. Biol. DOI: 10.1021/acschembio.5b00889.
  2. Huang, F.; Nie, Y.; Ye, F.; Zhang, M.; Xia, J.* Site selective Azo coupling for peptide cyclization and affinity labeling of an SH3 protein. Bioconjugate Chem. 2015, 26, 1613-1622.
  3. Ng, T. B.; Cheung, R. C.; Wong, J. H.; Wang, Y.; Ip, D. T.; Wan, D. C.; Xia, J. Antiviral activities of whey proteins. Appl. Microbiol. Biotechnol. 2015, 99, 6997-7008.
  4. Yu, Y.; Wang, J.; Liu, J.; Ling, D.; Xia, J.* Functional assembly of protein fragments induced by spatial confinement. PLoS One. 2015, 10, e0122101.
  5. Kang W.; Liu, J.; Wang, J.; Nie, Y.; Guo, Z.; Xia, J.*
    “Cascade Biocatalysis by Multienzyme-Nanoparticle Assemblies”
    Bioconjugate Chem., 2014, 25, 1387-1394.
  6. Lu, Y.; Huang, F.; Wang, J.; Xia, J. *
    “Affinity-guided covalent conjugation reactions based on PDZ-peptide and Sh3-peptide interactions” 
    Bioconjugate Chem., 2014, 25, 989-999. [Featured on Cover] (†, equal contribution)
  7. Ling, D.; Gao, L.; Wang, J.; Shokouhimehr, Liu, J.; Yu, Y.; Hackett, M. J.; So, P-K.; Zheng, B.; Yao, Z.; Xia, J.*; Hyeon, T.*
    “A general strategy for site-direced enzyme immobilization by using NiO nanoparticle decorated mesoporous silica”
    Chem. Eur. J., 2014, 20, 7916-7921.
  8. Wang, J.; Yu, Y.; Xia, Xia, J. *
    “Short Peptide Tag for Covalent Protein Labeling Based on Coiled Coils”,
    Bioconjugate Chem., 2014, 25, 178-187. [Featured on Cover]
  9. Wang, J.; Nie, Y.; Lu, Y.; Liu, J.; Wang, J.; Fu, A.; Liu, T.; Xia, J.
    “The Assembly of Multivalent Protein Ligands and Quantum Dots: A Multifaceted Investigation”
    Langmuir, 2014, 30, 2161-2169. [Featured on Cover]
  10. Wang, J.; Xia, J.*
    “Preferential Binding of a Novel Polyhistidine Peptide Dendrimer Ligand on Quantum Dots Probed by Capillary Electrophoresis”
    Anal. Chem.201183, 6323-9.