Prof. LAM, Hon Ming
| Address: | Room 298A, Science Centre, CUHK (Office) |
| Room 298, Science Centre, CUHK (Lab) | |
| Phone: | (852) 2609-6336 (Off) / (852) 2609-8132 (Lab) |
| (852) 2609-8142 (AoE Lab) | |
| Fax: | (852) 2603-5646, (852) 2603-5745 |
| E-mail: | honming@cuhk.edu.hk |
Education
| 1992 | PhD (Molecular Biology and Biochemistry), Northwestern University, USA |
| 1987 | MPhil (Biology), The Chinese University of Hong Kong, Hong Kong |
| 1985 | BSc (Biology), The Chinese University of Hong Kong, Hong Kong |
Position
| 2002-present | Associate Professor (Dept of Biology, The Chinese University of Hong Kong, Hong Kong) |
| 1997-2001 | Assistant Professor (Dept of Biology, The Chinese University of Hong Kong, Hong Kong) |
| Concurrent Position | |
| 2008-present | Associate Director (State Key Laboratory for Agrobiotechnology, The Chinese University of Hong Kong) |
| 2006-present | Associate Director (Institute of Plant Molecular Biology & Agricultural Biotechnology, The Chinese University of Hong Kong) |
| 2006-present | Deputy Director (UGC Area of Excellence on Plant & Agricultural Biotechnology Center, The Chinese University of Hong Kong) |
| 1999-2006 | Deputy Director (UGC Area of Excellence on Plant & Fungal Biotechnology Center, The Chinese University of Hong Kong) |
| 2002-present | Hostel Warden (Daisy Li Hall, New Asia College, The Chinese University of Hong Kong) |
| 2000-present | Visiting Research Professor (Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, China) |
| 2006-present | Visiting Professor (Institute of Plant Sciences, Jilin University, China) |
Professional Activities:
| Editorial Board: | |
| 2004-present | Journal of Integrative Plant Biology (Acta Botanica Sinica) |
| 2006-present | Soybean Bulletin |
| Appointments in the following Professional Organizations: | |
| 2003-present | Chairman, Curriculum Development Institute and Hong Kong Examinations and Assessment Authority Joint Committee on Integrated Science (Senior Secondary) |
| 2002-present | Co-opted Member (Crop Farming Sub-Committee of the Advisory Committee on Agriculture and Fisheries, HKSAR) |
| 2001-present | Elected Council Member (Soybean Specialty Committee of The Crop Science Society of China) |
| 2005-present | Vice Secretariat (Soybean Specialty Committee of The Crop Science Society of China) |
| 2005-present | Member of Academic Council, Beijing Sub-center of the National (China) Center for Soybean Improvement |
| 2001-2003 | Co-opted Council Member (The Society of Hong Kong Scholars) |
| 2003-present | Elected Council Member and External Secretary (The Society of Hong Kong Scholars) |
| Co-inventor of the following US Patents: | |
| 1. | Plant nitrogen regulatory P-PII polypeptides (granted); Patent number: 6,822,079 (2004) |
| 2. | Plant nitrogen regulatory P-PII genes (granted); Patent number: 6,177,275 (2001) |
| 3. |
Plant glutamate receptors (granted); Patent number: 5,824,867 (1998); 5,981,703 (1999); 5,959,174 (1999); 6,451,546 (2002) |
Research Interest
| 1. | Molecular studies and manipulation of amino acid metabolisms in higher plants |
| 2. |
Functional genomics, molecular and biochemical studies of biotic and abiotic stresses in higher plants |
Representative Publications
| 1. | Cheung, M.-Y., Zeng, N.-Y., Tong, S.-W., Li, F.W.-Y., Xue, Y., Zhao, K.-J., Wang, C., Zhang, Q., Fu, Y., Sun, Z., Sun, S.S.-M. and Lam, H.-M. (2008) Constitutive expression of a rice GTPase activating protein induces defense responses. New Phytol. 179: 530-545. |
| 2. | Li, F.W.-Y., Shao, G.-H. and Lam, H.-M. (2008) Ectopic expression of GmPAP3 alleviates oxidative damage caused by salinity and osmotic stresses. New Phytol. 178: 80-91. |
| 3. | Cheung, M.-Y., Zeng, N.-Y., Tong, S.-W., Li, F.W.-Y., Zhao, K.-J., Zhang, Q., Sun, S.S.-M. and Lam, H.-M. (2007) Expression of a RING-HC protein from rice improves resistance to Pseudomonas syringae pv. tomato DC3000 in transgenic Arabidopsis thaliana. J. Exp. Bot. 58: 4147-4159. |
| 4. | Wan, T.-F., Shao, G.-H. Shao, Shan, X.-C., Zeng, N.-Y., and Lam, H.-M. (2006) Correlation between AS1 gene expression and seed protein contents in different soybean (Glycine max [L.] Merr.) cultivars. Plant Biol. 8: 271-276. |
| 5. | Li, W.-Y.F., Wong, F.-L., Tsai, S.-N., Phang, T.-H., Shao, G., and Lam, H.-M. (2006) Tonoplast located GmCLC1 and GmNHX1 from soybean enhance salt tolerance in transgenic Bright Yellow (BY)-2 cells. Plant Cell Environ. 29: 1122-1137. |
| 6. | Wu, C., Ma, Q., Yam, K.-M., Cheung, M.-Y., Xu, Y., Han, T., Lam, H.-M., and Chong, K.-C. (2006). In situ expression of the GmNMH7 gene is photoperiod-dependent in a unique soybean (Glycine max [L.] Merr.) flowering reversion system. Planta 223: 725-735. |
| 7. | Wong, H.-K., Chan, H.-K., Coruzzi, G., and Lam, H.-M. (2004) Correlation of ASN2 gene expression with ammonium metabolism in Arabidopsis thaliana. Plant Physiology 134: 332-338. |
| 8. | Liao, H., Wong, F.-L., Phang, T.-H., Cheung, M.-Y., Li, W.-Y.F., Shao, G., Yan, X., and Lam, H.-M. (2003) GmPAP3, a novel purple acid phosphatase-like gene in soybean induced by NaCl stress but not phosphorus deficiency. Gene 318: 103-111. |
| 9. | Lam, H.-M., Wong, P., Chan, H.-K., Yam, K.-M., Chen, L., Chow, C.-M., and Coruzzi, G. (2003) Expression of the ASN1 gene enhances nitrogen status in seeds of Arabidopsis thaliana. Plant Physiology 132: 926-935. |
| 10. | Chiu, J., DeSalle, R., Lam, H.-M., Meisel, L. and Coruzzi, G. (1999) Molecular evolution of glutamate receptors: A primitive mechanism that existed before plants and animals diverged. Molecular Biology and Evolution 16: 826-838. |
| 11. | Lam, H.-M., Chiu, J., Hsieh, M.-H., Meisel, L., Oliveira, I.C., Shin, M. and Coruzzi, G. (1998) Glutamate receptor genes in plants. Nature 396: 125-126. |
| 12. | Lam, H.-M., Hsieh, M.-H. and Coruzzi, G. (1998) Reciprocal regulation of distinct asparagine synthetase genes by light and metabolites in Arabidopsis thaliana. Plant Journal 16: 345-353. |
| 13. | Hsieh, M.-H., Lam, H.-M., Van de Loo F.J. and Coruzzi, G. (1998) A PII-like protein in Arabidopsis: putative role in nitrogen sensing. Proceeding National Academy Sciences U.S.A. 23: 13965-13970. |
| 14. | Lam, H.-M., Coschigano, K., Oliveira, I.C., Melo-Oliveira, R. and Coruzzi, G. (1996) The molecular-genetics of nitrogen assimilation into amino acids in higher plants. Annual Review of Plant Physiology and Plant Molecular Biology 47: 569-593. |
| 15. | Lam, H.-M., Coschigano, K., Schultz, C., Ngai, N., Oliveira, R., Hsieh, M., Oliveira, I. and Coruzzi, G. (1995) Nitrogen assimilation into amide amino acids in Arabidopsis thaliana. Plant Cell 7: 887-898. |
| 16. | Lam, H.-M., Peng, S. and Coruzzi, G. (1994) Metabolic control of asparagine synthetase gene expression in Arabidopsis thaliana. Plant Physiology 106: 1347-1357. |
| 17. | Lam, H.-M. and Winkler, M.E. (1992) Characterization of the complex pdxH-tyrS operon of Escherichia coli K-12 and pleiotropic phenotypes caused by pdxH insertion mutations. Journal of Bacteriology 174:6033-6045. |
| 18. | Lam, H.-M., Tancula, E., Dempsey, W.B. and Winkler, M.E. (1992) Suppression of insertions in the complex pdxJ operon of Escherichia coli K-12 by lon and other mutations. Journal of Bacteriology 174: 1554-1567. |
| 19. | Lam, H.-M. and Winkler, M.E. (1990) Metabolic relationship between pyridoxine (vitamin B6) and serine biosynthesis in Escherichia coli K-12. Journal of Bacteriology 172: 6518-6528. |
Research Grants
| Hong Kong University Grant Council (UGC) Area of Excellence (AoE) | |
| 2007-2010 | Plant and Agricultural Biotechnology - HK$25,000,000 (co-investigator and deputy director) |
| 2000-2006 | Plant and Fungal Biotechnology - HK$38,823,000 (co-investigator and deputy director) |
| Research Grants Council (RGC) Earmarked Grants | |
| 2004-2006 | Characterization and Functional Analysis of a Novel NaCl-Inducible Purple Acid Phosphatase-Like Gene - HK$939,968 |
| 2002-2004 | Gene Regulation in the Signal Transduction Pathways of Broad-Spectrum Bacterial Blight Resistance Loci in Rice - HK$876,000 |
| 2000-2002 | Sink-source Relationship during Seed Development in Arabidopsis thaliana - Molecular Regulation of Aspartate Family Amino Acids - HK$1,062,600 |
| 1999-2002 | Molecular and Biochemical Characterization of a Salt-tolerant Soybean Variety - HK$709,500 |
| 1998-2001 | Asparagine Synthetase Genes: Their Roles in Plant Growth and Development - HK$1,032,000 |
| Industrial Support Fund | |
| 1998-2001 | Production of High Value Pharmaceutical Proteins in Transgenic Seeds - HK$5,292,000 (co-investigator and deputy co-ordinator) |
| France/Hong Kong Joint Research Scheme | |
| 1999-2000 | Production of Vaccines against Lymphocytic Choriomeningitis Virus (LCMV) in Transgenic Plants - HK$30,000 |
| Ho Sin Hang Education Endowment Fund | |
| 1997-1998 | Reclaiming the Salty Lands for Agriculture - HK$250,000 |
| CUHK Science Faculty Dicretionary Fund for Excellence | |
| 1999-2000 | Plant Gene Signaling - HK$100,000 |
Awards
| 2007 | Second-Class Award for Science and Technology, Zhejiang Province, PRC: Establishment and Large Scale Application of an Efficient and Safe System for Transgenic Rice Technology. |
| 2005-2006 | Exemplary Teaching Award, Faculty of Science, The Chinese University of Hong Kong |
| 2004 | Foreign Expert, 2004 Program for Introducing Foreign Experts on Technology and Management, State Administration of Foreign Experts Affairs, P.R.C. |
| 2001 | Second-Class Award for Scientific and Technological Achievements, Beijing City, PRC: Research and Application of Salt Tolerance Study in Soybean. |
| 1999-2000 | Exemplary Teaching Award, Faculty of Science, The Chinese University of Hong Kong |
| 1998 | Most Cordial Teacher Award, elected by students from Department of Biology, The Chinese University of Hong Kong |
| 1998 | Award of Excellence in Presentation, 6th Pacific Rim Biotechnology Conference and BioExpo '98 |
| 1992 | Raymond W Sarber Award, American Society for Microbiology |
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