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Key Members

Prof. Winnie Yeo

Department of Clinical Oncology
Chinese University of Hong Kong


Research Interest :

Breast cancer, Liver cancer, Hepatitis B virus-related complications during cancer treatment

Selected Publications on Women's Health :

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1. Yeo, W., Mo, F.K.F., Suen, J.J.S., Ho, W.M., Chan, S.L., Lau, W., Koh, J., Yeung, W.K., Kwan, W.H., Lee, K.K.C., Mok, T.S.K., Poon, A.N.Y., Lam, K.C., Hui, E.K., Zee., B. (2009) A randomized study of aprepitant, ondansetron and dexamethasone for chemotherapy-induced nausea and vomiting in Chinese breast cancer patients receiving moderately emetogenic chemotherapy. Breast Cancer Research and Treatment 113(3): 529. <Enter>
2. Wong, N., Yeo, W., Wong, N.L.Y., Wong, W.L., Chan., K.Y.Y., Mo, F.K.F., Koh, J., Chan, L., Chan, A.T.C., Lai, P.B.S., Johnson, P.J., To, K.F. (2009) TOP2A Expression in Hepatocellular Carcinoma Correlates with Early Age Onset, Shorter Survival but can Enhance Chemo-sensitisation by Etoposide. International journal of cancer 124(3): 644.
3. Bernhard, J., Zahrieh, D., Zhang, J.J., Martinelli, G., Basser, R., Hu¨rny, C., Forbes, J.F., Aebi, S., Yeo, W., Thu¨rlimann, B., Green, M.D., Colleoni, M., Gelber, R.D., Castiglione-Gertsch, M., Price, K.N., Goldhirsch, A., Coates, for the International Breast Cancer Study Group (IBCSG). (2008) Quality of life and quality-adjusted survival (Q-TWiST) in patients receiving dose-intensive or standard dose chemotherapy for high-risk primary breast cancer. British Journal of Cancer 98: 25. <Enter>
4. Chan, H.L.Y., Tse, C.H., Mo, F.K.F., Wong, V.W.S., Wong, G.L.H., Chan, S.L., Yeo, W., Sung, J.J.Y., Mok, T.S.K. (2008) High viral load and hepatitis b virus subgenotype Ce are associated with increased risk of hepatocellular carcinoma. Journal of Clinical Oncology 26(2): 177. <Enter>
5. Qiu, G.H., Salto-Tellez, M., Ross, J.A., Yeo, W., Cui, Y., Wheelhouse, N., Chen, G.G., Harrison, D., Lai, P., Tao, Q., Hooi, S.C. (2008) The tumor suppressor gene DLEC1 is frequently silenced by DNA methylation in hepatocellular carcinoma and induces G1 arrest in cell cycle. Journal of Hepatology 48(3): 433. <Enter>
6. Yu, S.C.H., Leung, T., Lau, W., Lee, N., Hui, E.P., Yeo, W., Lai, P.S.B., Mok, T.S.K. (2008) A comparison of three transarterial lipiodol-based formulations for hepatocellular carcinoma: in vivo biodistribution study in humans. CardioVascular and Interventional Radiology 31(2): 289. <Enter>
7. Yu S.C., Hui E.P., Wong J, Wong H, Mo F, Ho S.S, Wong Y.Y, Yeo W, Lai P.B, Chan A.T, Mok T.S. (2008) Transarterial ethanol ablation of hepatocellular carcinoma with lipiodol ethanol mixture: phase II study. Journal of Vascular and Interventional Radiology 19(1): 95 <Enter>
8. Mak, S.S., Yeo, W., Lee, Y.M., Mo, K.F., Tse, K.Y., Tse, S.M., Ho, F.P., Kwan, W.H. (2008) Predictors of lymphedema in patients with breast cancer undergoing axillary lymph node dissection in Hong Kong. Nursing Research 57(6): 416. <Enter>
9. Yeo W, Boyer M, Chung H.C, Ong S.Y.K, Lim R, Zee B, Ma B, Lam K.C, Mo F.K.F, Ng E.K.W, Ho R, Clarke S, Roh J.K, Beale P, Rha S.Y, Jeung H.C, Soo R, Goh B.C, Chan A.T.C. (2007) Irofulven as first line therapy in recurrent or metastatic gastric cancer: a phase II multicenter study by the Cancer Therapeutics Research Group (CTRG). Cancer Chemotherapy and Pharmacology 59: 295. <Enter>
10. Mok, T.S.K., Yeo, W., Johnson, P.J., Hui, P., Ho, W.M., Lam, K.C., Xu, M., Chak, K., Chan, A, Wong, H., Koh, J., Mo, F., Zee, B. (2007) A Double-Blind Placebo-Controlled Randomized Study of Chinese Herbal Medicine as Complimentary Therapy for Reduction of Chemotherapy-Induced Toxicity. Ann Oncol 18: 768. <Enter>
11. Yeo, W., Mo, F.K.F., Chan, S.L., Leung, N.W.Y., Hui, P., Lam, W.Y., Mok, T.S.K., Lam, K.C., Ho, W.M., Koh, J., Tang, J.W., Chan, A.T., Chan, P.K.S. (2007) Hepatitis B Viral Load Predicts Survival of Patients with Hepatocellular Carcinoma (HCC) Undergoing Systemic Chemotherapy. Hepatology 45: 1382. <Enter>
12. Chan, S., Tam, W., Yeo, W., Yu, M., Ng, D., Wong, A., Kwan, W., Yuen, P. (2007) A randomised controlled trial of prophylactic levonorgestrel intrauterine system in tamoxifen-treated women. Journal of Obstetrics and Gynaecology 114: 1510. <Enter>

13.

W Yeo , WH Kwan, PML Teo, S Nip, E Wong, LY Hin, PJ Johnson. Psychosocial impact of breast cancer surgeries in Chinese patients and their spouses. Psycho-Oncology 200 4 , 13:132-139.

14.

W Yeo , WM Ho, P Hui, PKS Chan, KC Lam, JJ Lee, PJ Johnson. Use of lamivudine to prevent hepatitis B virus reactivation during chemotherapy in breast cancer patient. Breast Cancer Research and Treatment 2004 ; 88: 209-215 .

15.

Chua MS, Mok TS, Kwan WH, Yeo W , Zee B. Knowledge, perceptions, and attitudes of Hong Kong Chinese women on screening mammography and early breast cancer management. Breast J. 2005 Jan-Feb;11(1):52-6.

16.

W. Yeo , W. M. Ho, P. Hui, K.C. Lam, B. Zee, W.H. Kwan, P.K.S. Chan, J.J. Lee, P.J. Johnson. Lamivudine can reduce hepatitis B reactivation in HBsAg seropositive breast cancer patients during chemotherapy. The 9 th Annual Symposium of the Hong Kong Cancer Institute. ˇ§Anti-Cancer Drug Development- From Bench to Bedside to Marketˇ¨, 19-20 March 2004 , abstract book, p39, #20.

17.

B Zee, W Yeo , MP Lai, C Koh, HM Chu. LM Lee . Chemotherapy-induced nausea affects patients' quality of life (QOL) more than chemotherapy-induced vomiting. The 9 th Annual Symposium of the Hong Kong Cancer Institute. ˇ§Anti-Cancer Drug Development- From Bench to Bedside to Marketˇ¨, 19-20 March 2004 , abstract book, p 40, #22.

18.

W. Yeo , W. M. Ho, P. Hui, K. C. Lam, B. Zee, W. H. Kwan, P. K. S. Chan, J. J. Lee, P. J. Johnson. Lamivudine for the prevention of hepatitis B reactivation in HBsAg cancer patients undergoing cytotoxic chemotherapy- A prospective study. 4th European Breast Cancer Conference, European Journal of Cancer 2004; 2(3): 142. 16-20 March 2004.

19.

RR Deuson, B Zee, T Mok, W Yeo , F Mo, A Lee. Impact of nausea and vomiting on quality pf life in patients receiving moderately to highly emetogenic chemotherapy in Hong Kong. ISOQOL 11th Annual Scientific Conference October 16-19, 2004, Hong Kong.

20. W Yeo , W-L Wong, N Wong, B Law, GM Tse, S Zhong. High frequency of promoter hypermethylation of RASSF1A in tumour and peritumoral tissue of breast cancer. Pathology 2005, 37(2): 125-130.
21. T.S.K. Mok, W. Yeo , P. Hui, W.M. Ho, K.C. Lam, Z.R. Pan, W.C. Au, M. Xu, T.C. Chan, K. Chak, P. Johnson, B Zee. A Double-blind Placebo-control Randomized Study of the Efficacy of Chinese Herbal Medicine (CHM) in Reduction of Cytotoxic Chemotherapy-induced toxicity. Proceedings of American Society of Clinical Oncology 2005; 23 (16S pt 1): 768s.
22. A Chang, J Beith, W Yeo , M Boyer, J Wong, S E Lim, A Chan. Phase I/II Study of Weekly Paclitaxel (P), UFT and Leucovorin in Patients with Metastatic Breast Cancer (MBC). A Cancer Therapeutic Research Group (CTRG) study. Proceedings of American Society of Clinical Oncology 2005; 23 (16S pt 1): 59s.