|
- Chronic endocrine disorders
15 August 2000
- Chronic endocrine disorders
CUHK Discovers Effective Way to Prevent Stomach
Cancer
Prolonged corticosteroid therapy
- Chronic endocrine disorders
A large-scale longitudinal collaborative research by the Faculty of
Medicine of The Chinese University of Hong Kong and the Peking University
Health Science Center (previously Beijing Medical University) discovers
that treatment of Helicobacter pylori can prevent gastric cancer at early
stages.
Gastric Cancer has the highest mortality among all cancers in China.
In Hong Kong, 1,017 new cases of gastric cancer were reported between 1995-1996.
585 patients died of stomach cancer in the same year. Among all the
risk factors studied, H. pylori infection has the strongest association
with gastric cancer, causing an increased risk of around six folds.
The association is even stronger in younger patients.
Extensive research at the Faculty of Medicine of The Chinese University
of Hong Kong has proved that antibiotics is effective for eradication of
H. pylori and cures gastric ulcers. Recently the Faculty of Medicine
of The Chinese University of Hong Kong and the Peking University Health
Science Center (previously Beijing Medical University) collaborated to
investigate the effect of treatment of H. pylori infection on the prevention
of gastric cancer. Researchers examined more than 1,000 subjects
in Yantai, a high prevalence area of gastric cancer. Among patients
who harboured H. pylori infection, half received a one-week course of antibiotics
to eradicate the bacteria, and the other received placebo. On follow-up
one year later, inflammation of the stomach dramatically improved in the
group who received antibiotics. Severe inflammation of the stomach
may develop into gastric cancer. The study also found that progression
of pre-malignant changes, i.e. gastric atrophy and intestinal metaplasia,
is also reduced in those who had successful eradication of H. pylori.
These results indicate that the testing for and eradicating H. pylori
is effective in preventing gastric cancer and have profound implications
to the treatment of the disease. The study was published in the July
issue of "Gastroenterology".
|