CHAN Wing Hung Anthony(陳永鴻)

BMedSc (Hons), MBChB, FRCPA, FHKCPath, FHKAM (Pathology)

Dr. Anthony Chan graduated from the Chinese University of Hong Kong and obtained his basic medical science degree and medical degree in 2000 and 2002, respectively. He completed his postgraduate pathology training at Prince of Wales Hospital, and received the fellowships from Royal College of Pathologists of Australasia and Hong Kong College of Pathologists in 2009 and 2010, respectively. He undertook a hepatopathology fellowship in the Newcastle University under the guidance of the world-renowned hepatopathologist, Prof. Alastair Burt in 2011.

Dr. Chan has been working in Department of Anatomical and Cellular Pathology, Prince of Wales Hospital all along and joined the university in January 2015. He is currently a clinical associate professor in the department, and also an honorary associate consultant pathologist at Prince of Wales Hospital. He has special interests in liver and gastrointestinal pathologies in both tumorous and non-tumorous diseases. He actively participated national and international academic activities. He has been invited to provide lectures in various pathology meetings in mainland China and overseas. He has been appointed as a committee member of Youth Committee of the Chinese Pathologist Association since September 2015. He also serves Education Committee of Hong Kong College of Pathologists as special coordinator (anatomical pathology) and vice chairman since 7/2012 and 1/2014, respectively.

Dr. Chan has been actively involving in research projects and collaborating with scientists and clinicians, and is a co-author of an atlas of liver pathology and a number of articles in peer-reviewed journals (Link). His ongoing active research projects:

1. Clinical significance and pathogenesis of histological variants of hepatocellular carcinoma
2. Clinical relevance of immunological aspects in hepatocellular carcinoma
3. Clinical applicability of the Albumin-Bilirubin (ALBI) score in hepatocellular carcinoma and non-tumorous liver disease
4. Digital image analysis of non-tumorous liver of patients with hepatocellular carcinoma
5. Molecular alterations of colonic serrated polyps

Selected Publications

Chan AW , Chong CC, Mo FK, Wong J, Yeo W, Johnson PJ, Yu S, Lai PB, Chan AT, To KF, Chan SL. Incorporating albumin-bilirubin grade into the cancer of the liver Italian program system for hepatocellular carcinoma. J Gastroenterol Hepatol 2017;32;221-228.

Sang W, Chan SL, Chan AW. Comments on "Proposal and validation of a new model to estimate survival for hepatocellular carcinoma patients". Eur J Cancer 2016;68;203-205.

Chan AW, Yu S, Yu YH, Tong JH, Wang L, Tin EK, Chong CC, Chan SL, Wong GL, Wong VW, Chan HL, Lai PB, To KF. Steatotic hepatocellular carcinoma: a variant associated with metabolic factors and late tumour relapse. Histopathology 2016;69;971-984.

Chan AW, Wong GL, Chan HY, Tong JH, Yu YH, Choi PC, Chan HL, To KF, Wong VW. Concurrent fatty liver increases risk of hepatocellular carcinoma among patients with chronic hepatitis B. J Gastroenterol Hepatol 2016.

Chan AW, Leung HH, Chong CC, Chan SL. Validating the ALBI grade: Its current and future use in HCC prognostication. J Hepatol 2016.

Chan AW, Kumada T, Toyoda H, Tada T, Chong CC, Mo FK, Yeo W, Johnson PJ, Lai PB, Chan AT, To KF, Chan SL. Integration of albumin-bilirubin (ALBI) score into Barcelona Clinic Liver Cancer (BCLC) system for hepatocellular carcinoma. J Gastroenterol Hepatol 2016;31;1300-1306.

Chan AW, Chong CC, Mo FK, Wong J, Yeo W, Johnson PJ, Yu S, Lai PB, Chan AT, To KF, Chan SL. Applicability of albumin-bilirubin-based Japan integrated staging score in hepatitis B-associated hepatocellular carcinoma. J Gastroenterol Hepatol 2016;31;1766-1772.

Leung HH, Cho CC, Chan AW. A pancreatic mass with multiple hepatic lesions. Clin Gastroenterol Hepatol 2015;13;e3-4.

Lee RK, Griffith JF, Ng AW, Ying Tam HK, Chan AW. Non-Hodgkin's Lymphoma of the Knee: A Case Report. Iran J Radiol 2015;12;e7583.

Chan SL, Chan AW. Development of Serum DHCR24 Antibody as a Marker for Hepatocellular Carcinoma: The End of the Beginning. EBioMedicine 2015;2;497-498.

Chan RC, Chu CM, Chow C, Chan SL, Chan AW. A concurrent primary hepatic MALT lymphoma and hepatocellular carcinoma. Pathology 2015;47;178-181.

Chan AW, Tong JH, Pan Y, Chan SL, Wong GL, Wong VW, Lai PB, To KF. Lymphoepithelioma-like hepatocellular carcinoma: an uncommon variant of hepatocellular carcinoma with favorable outcome. Am J Surg Pathol 2015;39;304-312.

Chan AW, Chan SL, Wong GL, Wong VW, Chong CC, Lai PB, Chan HL, To KF. Prognostic Nutritional Index (PNI) Predicts Tumor Recurrence of Very Early/Early Stage Hepatocellular Carcinoma After Surgical Resection. Ann Surg Oncol 2015;22;4138-4148.

Chan AW, Chan SL, Mo FK, Wong GL, Wong VW, Cheung YS, Chan HL, Yeo W, Lai PB, To KF. Albumin-to-alkaline phosphatase ratio: a novel prognostic index for hepatocellular carcinoma. Dis Markers 2015;2015;564057.

Chan AW, Chan RC, Wong GL, Wong VW, Choi PC, Chan HL, To KF. New simple prognostic score for primary biliary cirrhosis: Albumin-bilirubin score. J Gastroenterol Hepatol 2015;30;1391-1396.

Chan AW, Tong JH, Sung MY, Lai PB, To KF. Epstein-Barr virus-associated lymphoepithelioma-like cholangiocarcinoma: a rare variant of intrahepatic cholangiocarcinoma with favourable outcome. Histopathology 2014;65;674-683.

Chan AW, Tong JH, Chan SL, Lai PB, To KF. Expression of stemness markers (CD133 and EpCAM) in prognostication of hepatocellular carcinoma. Histopathology 2014;64;935-950.

Chan AW, Cheung YS, Lee KF. A rare tumor of the common hepatic duct causing biliary obstruction. Clin Gastroenterol Hepatol 2014;12;e29-30.

Chan AW, Chau HH, Ng SS. A rare cause of protein-losing enteropathy. Clin Gastroenterol Hepatol 2014;12;e49-50.

Chan AW, Chan RC, Wong GL, Wong VW, Choi PC, Chan HL, To KF. Evaluation of histological staging systems for primary biliary cirrhosis: correlation with clinical and biochemical factors and significance of pathological parameters in prognostication. Histopathology 2014;65;174-186.

Chan AW, Tong JH, Lo SH, To KF. An uncommon insertion mutation in exon 19 of EGFR showed stable disease after TKI treatment. J Thorac Oncol 2013;8;e107-108.

Chan AW, Mak SM, Chan GP. Benign epithelioid schwannoma of intraparotid facial nerve. Pathology 2011;43;280-282.

Chan AW, Hou SS, Lai FM. Renal myxoid tumour of uncertain malignant potential. Pathology 2011;43;287-289.

Chan AW, Chan CK, Chiu Y, Yip SK, Lai FM, To KF. Primary perivascular epithelioid cell tumour (PEComa) of the urinary bladder. Pathology 2011;43;746-749.