Anthony W. I. LO (羅穎業)

B Med Sc(CUHK), MB ChB(CUHK), Ph D(Melbourne)

Current research interests:

• Telomere and centromere chromatin in eukaryotes.
• Complex N-linked glycans in gastric cancers.
• Pathology of SARS-CoV infection.

Recent publications from the group:

Tse GM, To KF, Chan PK, Lo AW, Ng KC, Wu A, Lee N, Wong HC, Mak SM, Chan KF, Hui DS, Sung JJ, Ng HK. Pulmonary pathological features in coronavirus associated severe acute respiratory syndrome (SARS). J Clin Pathol. 2004;57:260-5

Tse GM, Hui PK, Ma TK, Lo AW, To KF, Chan WY, Chow LT, Ng HK. Sputum cytology of patients with severe acute respiratory syndrome (SARS). J Clin Pathol. 2004;57:256-9

Lo AW, Chow LT, To KF, Yu MY. Gastric glomangiomyoma: a pedunculated extramural mass with a florid angiomyomatous pattern. Histopathology 2004;44:297-8

To KF, Tong JH, Chan PK, Au FW, Chim SS, Chan KC, Cheung JL, Liu EY, Tse GM, Lo AW, Lo YM, Ng HK. Tissue and cellular tropism of the coronavirus associated with severe acute respiratory syndrome: an in-situ hybridization study of fatal cases. J Pathol. 2004;202:157-63

Lo AW, Tse GM, Chu WC, Chan AB. Pulmonary tumour microembolism clinically mimicking alveolitis. J Clin Pathol. 2003;56:866-7

Craig JM, Wong LH, Lo AW, Earle E, Choo KH. Centromeric chromatin pliability and memory at a human neocentromere. EMBO J. 2003;22:2495-504

Lo AW, Sabatier L, Fouladi B, Pottier G, Ricoul M, Murnane JP. DNA amplification by breakage/fusion/bridge cycles initiated by spontaneous telomere loss in a human cancer cell line. Neoplasia 2002;4:531-8

Lo AW, Craig JM, Saffery R, Kalitsis P, Irvine DV, Earle E, Magliano DJ, Choo KH. A 330 kb CENP-A binding domain and altered replication timing at a human neocentromere. EMBO J. 2001;20:2087-96

Lo AW, Magliano DJ, Sibson MC, Kalitsis P, Craig JM, Choo KH. A novel chromatin immunoprecipitation and array (CIA) analysis identifies a 460-kb CENP-A-binding neocentromere DNA. Genome Res. 2001;11:448-57

Lo AW, Longmuir DF, Fowler KJ, Kalitsis P, Choo KH. Assignment of the centromere protein H (Cenph) gene to mouse chromosome band 13D1 by in situ hybridization and interspecific backcross analyses. Cytogenet Cell Genet. 2000;90:56-7

Slater HR, Nouri S, Earle E, Lo AW, Hale LG, Choo KH. Neocentromere formation in a stable ring 1p32-p36.1 chromosome. J Med Genet. 1999;36:914-8

Lo AW, Liao GC, Rocchi M, Choo KH. Extreme reduction of chromosome-specific alpha-satellite array is unusually common in human chromosome 21. Genome Res. 1999;9:895-908

Please also see my recent publications at PubMed

E-mail : awilo@cuhk.edu.hk