Ho-keung NG（吳浩強）

MB ChB (Edin.), MD, FRCPath, FRCPA, FCAP, FFPathRCPI, MIAC, FHKC Path

H.K. Ng is Department Chairman and Chief of Service. His interests are in the molecular genetics of brain tumours, especially medulloblastoma and glioma and the use of neural and embryonic stem cell in cell therapy.

He is also Associate Dean (Education) of the Faculty of Medicine and Vice Director of the State Key Laboratory of Oncology (South China), China. He is on the Editorial Boards of Pathology, Neuropathology and Applied Neurobiology, Acta Neuropathologica, Clinical Neuropathology, Chinese Journal of Neuro-oncology and Chinese Journal of Pathology. He was a member of the Consensus Group of the 2007 WHO classification of the brain tumours. His major international professional activities are : a Vice President of the International Academy of Pathology since 1999, Chairman of the Association of Directors of Pathology of China (http://www.acp.cuhk.edu.hk/adpc) since 1998, Secretary of the Medical Education Association of China, Taiwan and Hong Kong (http://www.mea.org.hk) and a Council Member of Association of the Study of Medical Education (ASME) of UK. Locally, he is the Chairman of the Licentiate Examination Subcommittee of the Licentiate Committee, Hong Kong Medical Council.

Recent Publications from the group:

Ho CYS, Murnane JP, Yeung AKY, Ng HK, Lo AWI. Telomere acquired distinct heterochromatin characteristics during siRNA-induced RNAi in mouse cells. Current Biology, in press

Fong SP, Tsang KS, Chan ABW, Lu G, Poon WS, Li K, Baum LW, Ng HK. Trophism of neural progenitor cells to enbryonic stem cells : neural induction and transplantation in a mouse ischemic stroke model. Journal of Neuroscience Research 2007 Jul;85(9):1851-62

Li KK, Pang JC, Chung NY, Ng YL, Chan NH, Zhou L, Poon WS, Ng HK. EMP3 overexpression is associated with oligodendroglial tumors retaining chromosome arms 1p and 19q. International Journal Cancer. 2007; 120:947-50

Cheng SH, Ng MH, Lau KM, Liu HS, Chan JC, Hui AB, Lo KW, Jiang H, Hou J, Chu RW, Wong WS, Chan NP, Ng HK. 4q loss is potentially an important genetic event in MM tumorigenesis : identification of a tumor suppressor gene regulated by promoter methylation at 4q13.3 platelet factor 4. Blood 2007; 109:2089-99

Hui AB, Takano H, Lo KW, Kuo WL, Lam CN, Tong CY, Chang Q, Gray JW, Ng HK. Identification of a novel homozygous deletion region at 6q23.1 in medulloblastomas using high-resolution array comparative genomic hybridization analysis. Clin Cancer Res. 2005; 11:4707-16

Dong Z, Pang JS, Ng MH, Poon WS, Zhou L, Ng HK. Identification of two contiguous minimally deleted regions on chromosome 1p36.31-p36.32 in oligodendroglial tumours. Br J Cancer. 2004;91:1105-11

Dong SM, Pang JCS, Hu J, Zhou LF, Ng HK. Transcriptional inactivation of TP73 expression in oligodendroglial tumors. International Journal of Cancer 2002; 98:370-375

Yin XL, Pang JCS, Ng HK. Identification of a region of homozygous deletion on 8p22-23.1 in medulloblastoma. Oncogene 2002; 21:1461-1468

Please also see my recent publications at PubMed

E-mail : hkng@cuhk.edu.hk