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HISTOPATHOLOGY AND CYTOPATHOLOGY
| TEST NAME | SPECIMEN/REQUIREMENT |
| Routine Histopathology | |
| Small Biopsy, single | Fixed in 10% buffered formalin. |
| Small Biopsy, multiple sites | Fixed in 10% buffered formalin. |
| Surgical Large Specimen, single | Fixed in 10% buffered formalin. |
| Special Biopsies | |
| Liver Biopsy, with Histochemistry Panel | Fixed in 10% buffered formalin. |
| Muscle Biopsy, with Enzyme / Histochemical Staining Panel | Fresh specimen required. Specimen should be rest on a piece of moist filter paper and wrapped by gauze wetted with normal saline, and sent to laboratory immediately.(Advance booking is required.) |
| Renal Biopsy, with IF Profile | Fresh specimen required. Specimen should be placed in normal saline and sent to laboratory as soon as possible. |
| Skin Biopsy, with IF Profile | Fresh specimen required. Specimen should be wrapped by gauze wetted with normal saline and sent to laboratory as soon as possible. |
| Rectal Biopsy, with Histochemistry for Ganalionic Cells | Fresh specimen required. Specimen should be wrapped by gauze wetted with normal saline and sent to laboratory as soon as possible . |
| Nerve Biopsy, with Teased Fibre Preparation & EM | Fresh specimen required. Specimen should be rest on a piece of moist filter paper and wrapped by gauze wetted with normal saline, and sent to laboratory immediately.(Advance booking is required.) |
| Molecular Tests | |
| HPV DNA Typing for Autocyte Prep | Fixed in specialized preservative (SurePath Preservative Fluid). |
| Breast Tissue with Hormone Receptors and Prognostic Markers | NFB fixed paraffin section. |
| Apolipoproptein E Genotyping | NFB fixed paraffin section. |
| Paraffin Block Molecular Tests for TB | NFB fixed paraffin section. |
| MGMT | NFB fixed paraffin section. |
| Lymphoma Typing (Frozen / Paraffin Marker Panel) | NFB fixed paraffin section. |
| Lymphoma Genotype | NFB fixed paraffin section. |
| 1p19q | NFB fixed paraffin section. |
| HER-2 FISH for Breast Cancers (FDA approved) | NFB fixed paraffin section. |
| Epidermal Growth Factor Receptor Immuno Stain | NFB fixed paraffin section. |
| Epidermal Growth Factor Receptor mutation test (EGFR) | NFB fixed paraffin section or frozen section. |
| KRAS Mutation Test | NFB fixed paraffin section. |
| Special Tests | |
| Decalcification | NFB fixed paraffin section. |
| Histochemical Staining (Special / Enzyme Stains) | Fresh specimen required. |
| Immunohistochemical Markers, Paraffin or Frozen | NFB fixed paraffin section or frozen section depending on antibodies used. |
| Teased Fibre Preparation for Nerve Biopsy | NFB fixed paraffin section. |
| Immunoelectron Microscopy, examined | Fixed in 2.5% glutaraldehyde. |
| In-Situ Hybridization (ISH), e.g. for EBER | NFB fixed paraffin section. |
| Hormone Receptor | NFB fixed paraffin section. |
| Electron Microscopy | Fixed in 2.5% glutaraldehyde |
| Transmission Electron Microscopy, grids examined | Fixed in 2.5% glutaraldehyde |
| Other Molecular Pathology Tests, e.g. PCR, Southern Blot, etc. | NFB fixed paraffin section. |
| Cytology | |
| Cervical Smear (ThinPrep Method) | Specialized preservative (ThinPrep PreservCyt @Solution). |
| Cervical Smear (Autocyte, ThinPrep) | Specialized preservative (SurePath Preservative Fluid). |
| Semen Analysis | Fresh specimen and advance booking required. |
| Sputum | Fresh specimen required. |
| Non-Gynae (e.g. Sputum, Bronchial, Body Fluids, etc.) | Fresh specimen or mixed with equal volume of 50% alcohol. |
| Joint fluid | Fresh specimen required. |
| FNA, sampled by clinician and sent to laboratory, single | Fixed in 25% saline-alcohol (fixed in 90-95% alcohol for smears). |
| Miscellaneous Items | |
| Slide Consultation (Case Review, Surgical or Cytology) | No specific requirement |
| *** Please call 2632-3949 for advance booking. |