Biography
Dr Timothy Lai is Honorary Clinical Associate Professor of the Department of
Ophthalmology & Visual Sciences and is the Coordinator of the
Medical Retina and Uveitis service at the Hong Kong Eye Hospital. Dr
Lai graduated from the medical school of the University of Sydney
and was later awarded the postgraduate Doctor of Medicine degree by
the Chinese University of Hong Kong. He has been awarded the Li Po
Chun Charitable Trust overseas training scholarship and received
further training in vitreoretinal diseases in the United States. He
has published more than 120 papers in international peer-reviewed
journals. Dr Lai has received a number of awards including the
Nakajima Award of the Asia-Pacific Academy of Ophthalmology in 2008
and Hong Kong’s Ten Outstanding Young Person Selection in 2008. Dr
Lai serves in the editorial boards of 5 journals and is an active
reviewer in more than 20 ophthalmic and visual sciences journals and
3 research grants. He is currently the Editor-in-Chief of the Hong
Kong Journal of Ophthalmology, the Regional Secretary representing
Hong Kong in the Asia-Pacific Academy of Ophthalmology, and is an
international council member representing China in the International
Ocular Inflammation Society.
Research interests
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Medical Retina and Macular Diseases Main research areas include the use of photodynamic therapy (PDT)
and anti-vascular endothelial growth factors (anti-VEGF) in the
treatment of various macular diseases including age-related macular
degeneration, myopic choroidal neovascularization, polypoidal
choroidal vasculopathy, and central serous chorioretinopathy. Other
main research areas include surgical treatment of macular hole and
epiretinal membrane, and the evaluation of genetic mutations in
patients with various hereditary retinal or macular diseases.
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Visual Electrophysiology Main research areas include the application of various visual
electrophysiological techniques including electrooculography (EOG),
full-field electroretinography (ffERG), multifocal
electroretinography (mfERG), pattern electroretinography (PERG), and
visual evoked potentials (VEP), in particularly the role of
multifocal electroretinography in the assessment of retinal toxicity
associated with different pharmacological therapies.
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Uveitis Research areas include the study of intraocular inflammation more
prevalent in Chinese patients such as Vogt-Koyanagi-Harada syndrome,
and the evaluation of genetic variations in Chinese patients with
uveitis.
Representative publications
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Lai TY, Wong VW, Leung GM. Is ophthalmology
evidence-based? A clinical audit of the emergency unit of a regional
eye hospital. Br J Ophthalmol 2003;87:385-90.
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Lai TY, Chan WM, Lam DS. Transient reduction in retinal
function revealed by multifocal electroretinogram following
photodynamic therapy. Am J Ophthalmol 2004;137:826-833.
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Lai TY, Chan WM, Li H, Lai RY, Lam DS. Multifocal
electroretinographic changes in patients on hydroxychloroquine
therapy: a longitudinal study. Am J Ophthalmol 2005;140:794-807.
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Lai TY, Leung GM, Wong VW, Lam RF, Cheng CO, Lam DS. How
evidence-based are publications in clinical ophthalmic journals?
Invest Ophthalmol Vis Sci 2006;47:1831-1838.
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Lai TY, Chan WM, Li H, Lai RYK, Liu DT, Lam DS. Safety
enhanced photodynamic therapy with half dose verteporfin for chronic
central serous chorioretinopathy: a short term pilot study. Br J
Ophthalmol 2006;90:869-874.
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Lai TY, Chan WM, Lai RY, Ngai JW, Li H, Lam DS. The
clinical applications of multifocal electroretinography: a
systematic review. Survey of Ophthalmology 2007;52:61-96.
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Lai TY, Ng TK, Tam PO, Yam GH, Ngai JW, Chan WM, Liu DT,
Lam DS, Pang CP. Genotype-phenotype analysis of Biett’s crystalline
dystrophy in patients with CYP4V2 mutations. Invest Ophthalmol Vis
Sci 2007;48:5212-5220.
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Lai TY, Chan WM, Liu DT, Lam DS. Ranibizumab for retinal
angiomatous proliferation in neovascular age-related macular
degeneration. Graefe Arch Clin Exp Ophthalmol 2007;245:1877-1880.
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Lai TY, Chan RP, Chan CK, Lam DS. Effects of the Duration
of Initial Oral Corticosteroid Treatment on the Recurrence of
Inflammation in Vogt-Koyanagi-Harada Disease. Eye. 2008 Mar 28. [Epub
ahead of print]
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Lai TY, Chan WM, Liu DT, Luk OJ, Lam DS. Intravitreal
bevacizumab (Avastin) with or without photodynamic therapy for the
treatment of polypoidal choroidal vasculopathy. Br J Ophthalmol
2008;92:661-666.
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