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Biography and Research
interests
Dr. Barbara E. K. Klein is an active clinician in our glaucoma group
and also sees patients with other conditions as a comprehensive
ophthalmologist. She contributes to our resident teaching lectures
series and participates in teaching medical students and fellows in
other departments about general ophthalmology, ocular anatomy, and
age-related eye conditions. Dr. Klein is an active epidemiologic
researcher and is mainly funded by the National Eye Institute. She
also gives seminars about her research findings.
Representative publications
1. Klein BEK, Klein R, Lee KE. Incidence of age-related
cataract over a 10-year interval. The Beaver Dam Eye Study.
Ophthalmology 2002; 109:2052-57.
2. Schick JH, Iyengar SK, Klein BE, Klein R, Reading K,
Liptak R, Millard C, Lee KE, Tomany SC, Moore EL, Fijal BA, Elston
RC. A whole-genome screen of a quantitative trait of age-related
maculopathy in sibships from the Beaver Dam Eye Study. Am J Hum
Genet 2003; 72:1412-24.
3. Klein BEK, Klein R, Knudtson MD. Frailty and age-related
cataract. Ophthalmology 2006;113(12):2209-12.
4. Klein BEK, Klein R, Lee KE, Knudtson MD, Tsai MY. Markers
of inflammation, vascular endothelial dysfunction and age-related
cataract. Am J Ophthalmol 2006; 141:116-122.
5. Klein R, Klein BEK. The epidemiology of eye disease: from
glycemia to genetics. Invest Ophth Vis Sci 2006; 47(5):1747-1453.
6. Klein BEK, Klein R, Lee KE, Grady LM. Statin use and
incident nuclear cataract. JAMA 2006;295:2752-2758.
7. Thompson CL, Klein BEK, Klein R, Xu Z, Capriotti J, Joshi
T, Leontiev D, Lee KE, Elston RC, Iyengar SK. Complement factor H
and hemicentin-1 in age-related macular degeneration and renal
phenotypes. Hum Mol Genet Revision 2007; 16(17):2135-2148.
8. Klein BEK. Overview of epidemiologic studies of diabetic
retinopathy. Ophthalmic Epidemiol 2007; 14(4):179-83.
9. Klein BEK, Klein R. Lifestyle exposures and eye diseases
in adults. Am J Ophthalmol 2007;144:961-69.
10. Klein BEK, Klein R, Lee KE. Incidence of age-related
cataract over a 15-year interval. The Beaver Dam Eye Study.
Ophthalmology 2008; 115:477-82.
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