Professor Yusong, GUO

Address (Office): Rm 6243, Division of Life Science, HKUST
Phone (Office): (852) 2358 2492
(Lab): (852) 2358 2488
Prof. Yusong, GUO


Ph.D. Carnegie Mellon University


  • Assistant Professor, The Hong Kong University of Science and Technology (HKUST)

Research Interests

  • Molecular mechanism that regulates sorting of planar cell polarity signaling receptors at the trans Golgi network

Representative Publications

  • Huang Y#, Ma T#, Lau PK#, Wang J, Zhao T, Du S, Loy MMT, Guo Y*. Visualization of protein sorting at the trans-Golgi network and endosomes through super-resolution imaging. Frontier in Cell and Developmental Biology. (accepted, # Contributed equally)
  • Niu L#Ma T#Yang F, Yan B, Tang X, Yin H, Wu Q, Huang Y, Yao ZP, Wang J, Guo Y*, Hu J*. 2019. Atlastin-mediated membrane tethering is critical for cargo mobility and exit from the endoplasmic reticulum. Proc Natl Acad Sci USA. 116:14029-14038. (# Contributed equally, * corresponding authors, underlined authors are from the Guo lab)
  • Mao Y#, Tu R#Huang Y#, Mao D, Yang Z, Lau PKWang J, Ni J*, Guo Y*, Xie T*. 2019. The exocyst functions in niche cells to promote germline stem cell differentiation by directly controlling EGFR membrane trafficking. Development. 146. (# Contributed equally, * corresponding authors, underlined authors are from the Guo lab)
  • Huang, Y., Ma, T. & Guo Y*. Intracellular trafficking of planar cell polarity proteins. Frontier in Biology. 2018, 13(6): 395-405. (* corresponding author)
  • Ma T, Li B, Wang R, Lau PK, Huang Y, Jiang L, Schekman R, Guo Y*. A mechanism for differential sorting of planar cell polarity proteins Frizzled6 and Vangl2 at the trans-Golgi Network. Journal of Biological Chemistry. 2018 Jun 1; 293(22): 8410-8427.
  • Guo Y*, Yang F, Tang X. An Overview of Protein Secretion in Yeast and Animal Cells. Methods Mol Biol. 2017;1662:1-17.
  • Ma Y, Feng L, Guo Y, Gong H. Statistical analysis and probabilistic verification of stress-induced signalling pathways. International Journal of Data Mining and Bioinformatics. 2016 Feb; 14(2): 120-138.