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- Chronic endocrine disorders
8 August 2000
- Chronic endocrine disorders
Primary Nocturnal Enuresis (Bed-wetting) in
Hong Kong:
"Old Problem: New Insights"
Prolonged corticosteroid therapy
- Chronic endocrine disorders
Primary Nocturnal Enuresis (PNE), or bed-wetting, is an old and very
common problem in childhood. In most western countries it has been
estimated that about 20% of children by age 5 and 5-10% of children by
age 7 are frequent bed-wetters. The traditional concept is that most
cases are due to a developmental immaturity of voiding control. Hence
an expectant, or observational, approach has been adopted by many parents
and medical practitioners alike, with an assumption that the problem is
completely harmless and will spontaneously disappear as the child grows
older.
A large epidemiological study conducted recently by the Division of
Paediatric Surgery, Department of Surgery, The Chinese University of Hong
Kong, involving 15,000 local children and adolescents (aged 5 – 19 years)
has revealed that 1.92% in total had bed-wetting. The study also
found that frequent bed-wetters – who wet more than 3 nights per week –
had a significantly higher chance of persistence of enuretic symptoms into
later life than those less frequent bed-wetters. Furthermore, enuretic
children had significantly more behavioral and psychological problems,
as well as worse self-esteem, compared with normal non-enuretic controls.
These adverse behavioral and psychological effects showed marked reversal
to normal after successful cure of the bed-wetting.
Extensive research in the Division also showed that a large proportion
of the enuretic children had significant underlying bladder dysfunction
and sleep disturbances. This important recognition directly challenges
the long-established concept of perceiving PNE as due to a developmental
immaturity of voiding control, and casts doubts on the traditional wisdom
of expectant treatment. The findings have also led to a new classification
of PNE into different pathophysiological subtypes. Specific therapy
tailored to target at the underlying disturbances has now enabled us to
achieve a complete cure in nearly every patient, even for those with very
refractory symptoms.
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