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Dr Wai San CHEANG, Anna

 

SCI-indexed publications

 

  • Cheng CK, Shang W, Liu J, Cheang WS, Wang Y, Xiang L, Lau CW, Luo JY, Ng CF, Huang Y, Wang L (2022) Activation of AMPK/miR-181b Axis Alleviates Endothelial Dysfunction and Vascular Inflammation in Diabetic Mice. Antioxidants 11(6):1137 (17 pages).
  • Zhang X, Zhou C, Miao L, Tan Y, Zhou Y, Cheong MS, Huang Y, Wang Y, Yu H & Cheang WS (2021) Panax Notoginseng Protects against Diabetes-associated Endothelial Dysfunction: Comparison between Ethanolic Extract and Total Saponin. Oxidative Medicine and Cellular Longevity Volume 2021, Article ID 4722797, 10 pages.
  • Cheang WS, Wong WT, Wang L, Cheng CK, Lau CW, Ma RCW, Xu A, Wang N, Huang Y & Tian XY (2018) Resveratrol ameliorates endothelial dysfunction in diabetic and obese mice through sirtuin 1 and peroxisome proliferator-activated receptor δ.Pharmacological Research 139:384-394.
  • Xiang L, Wei J, Tian XY, Wang B, Chan W, Li S, Tang Z, Zhang H, Cheang WS, Zhao Q, Zhao H, Yang Z, Hong Y, Huang Y & Cai Z. (2017) Comprehensive analysis of acylcarnitine species in db/db mouse using a novel method of high resolution parallel reaction monitoring reveals widespread metabolic dysfunction induced by diabetes. Analytical Chemistry 89(19):10368-10375.
  • Cheang WS, Wong WT, Zhao L, Xu J, Wang L, Lau CW, Chen ZY, Ma RCW, Xu A, Wang N, Tian XY & Huang Y (2016) PPARδ Is required for exercise to attenuate endoplasmic reticulum stress and endothelial dysfunction in diabetic mice. Diabetes 66(2):519-528.

  • Tian XY, Wong WT, Lau CW, Wang YX, Cheang WS, Liu J, Lu Y, Huang H, Xia Y, Chen ZY, Mok CSD, Lau CM & Huang Y (2016) Melamine impairs renal and vascular function in rats. Scientific Reports 6:28041
  • Leung FP, Yung LM, Ngai CY, Cheang WS, Tian XY, Lau CW, Zhang Y, Liu J, Chen ZY, Bian ZX, Yao X & Huang Y (2016) Chronic black tea consumption improves endothelial function in ovariectomized rats. European Journal of Nutrition 55(5):1963-1972.

  • Cheang WS, Tian XY, Wong WT, Huang Y (2015) Peroxisome proliferator-activated receptors in cardiovascular diseases: experimental benefits and clinical challenges. British Journal of Pharmacology 172(23):5512-5522.
  • Wang X, Cheang WS, Yang H, Xiao L, Lai B, Zhang M, Ni J, Luo Z, Zhang Z, Huang Y & Wang N (2015) Nuciferine relaxes rat mesenteric arteries through endothelium-dependent and -independent mechanisms. British Journal of Pharmacology 172(23):5600-5618. (Co-first author)
  • Zhang Y, Liu J, Luo JY, Tian XY, Cheang WS, Xu J, Lau CW, Wang L, Wong WT, Wong CM, Lan HY, Yao XQ, Raizada MK & Huang Y (2015) Upregulation of angiotensin (1-7)-mediated signaling preserves endothelial function through reducing oxidative stress in diabetes. Antioxidants & Redox Signaling 23(11):880-892 with Cover Image of the Issue.
  • Xiang L, Cheang WS, Wang L, Lin S, Li Y, Huang Y & Cao Z (2015) Plasma metabolic signatures reveal regulatory effect of exercise training in db/db mice. Molecular BioSystems 11(9):2588-2596
  • Cheang WS, Ngai CY, Tam YY,  Tian XY, Wong WT, Zhang Y, Lau CW, Chen ZY, Bian ZX, Huang Y & Leung FP (2015) Black tea protects against hypertension-associated endothelial dysfunction through alleviation of endoplasmic reticulum stress. Scientific Reports 5:10340
  • Wu XL, *Cheang WS, Zhang DM, Li Y, Lau CW, Wang GC, Huang Y & Ye WC (2015) Antagonism of Ca2+ influx via L-type Ca2+ channels mediates the vasorelaxant effect of Catharanthus roseus-derived vindorosine in rat renal artery. Planta Medica 80(18)1672-1677.
  • Huang W, Cheang WS, Wang X, Lei L, Liu Y, Ma KY, Zheng F, Huang Y & Chen ZY (2014) Capsaicinoids but not their analog capsinoids lower plasma cholesterol and possess beneficial vascular activity. Journal of Agricultural and Food Chemistry 62(33):8415-8420
  • Cheang WS, Tian XY, Wong WT, Lau CW, Lee ST; Chen ZY, Yao X, Wang N & Huang Y (2014) Metformin protects endothelial function in diet-Induced obese mice by inhibition of endoplasmic reticulum stress through 5' adenosine monophosphate-activated protein kinase-peroxisome proliferator-activated receptor δ pathway. Arteriosclerosis, Thrombosis and Vascular Biology 34(4):830-6
  • Zhang Y, Liu J, Tian XY, Wong WT, Chen Y, Wang L, Luo JY, Cheang WS, Lau CW, Kwan KM, Wang N, Yao X & Huang Y (2014) Inhibition of bone morphogenic protein-4 restores endothelial function in db/db diabetic mice. Arteriosclerosis, Thrombosis and Vascular Biology 34(1):152-159
  • Cheang WS, Fang X, Tian XY (2013) Pleiotropic Effects of Peroxisome Proliferator-activated Receptor γ and δ in Vascular Diseases. Circulation Journal 77(11):2664-71.
  • Cheang WS, Lam MY, Wong WT, Tian XY, Zhu Z, Yao X & Huang Y (2013) Menthol relaxes rat aortae, mesenteric and coronary arteries by inhibiting calcium influx. European Journal of Pharmacology 702(1-3):79-84.
  • Tian XY, Wong WT, Wang N, Lu Y, Cheang WS, Liu J, Liu L, Liu Y, Lee SST, Chen ZY, Cooke JP & Huang Y (2012) PPARδ activation protects endothelial function in diabetic mice. Diabetes 61(12):3285-3293.
  • Zhang DM, Li Y, *Cheang WS, Lau CW, Lin SM, Zhang QL, Yao N, Wang Y, Wu X, Huang Y & Ye WC (2012) Cajaninstilbene acid relaxes rat renal arteries: roles of Ca2+ antagonism and protein kinase C-dependent mechanism. PLoS One 7(10):e47030. (*Co-first author)
  • Tian, XY, Wong WT, Xu A, Lu Y, Zhang Y, Wang L, Cheang WS, Wang Y, Yao X & Huang Y (2012) Uncoupling protein-2 protects endothelial dysfunction in diet-induced obese mice. Circulation Research 110:1211-1216.
  • Tian XY, Wong WT, Sayed N, Luo J, Tsang SY, Bian ZX, Lu Y, Cheang WS, Yao X, Chen ZY & Huang Y (2012) NaHS relaxes rat cerebral artery in vitro via inhibition of L-type voltage-sensitive Ca2+ channel. Pharmacological Research 65(20):239-246.
  • Cheang WS, Wong WT, Tian XY, Yang Q, Lee HK, He GW, Yao X & Huang Y (2011) Endothelial nitric oxide synthase enhancer AVE3085 restores endothelial function and reduces oxidative stress in type 2 diabetic db/db mice. Cardiovascular Research 92(2):267-275.
  • Cheang WS, Wong WT, Shen B, Lau CW, Tian XY, Tsang SY, Yao X, Chen ZY, Huang Y (2010) 4-Aminopyridine-sensitive K+ channels contributes to NaHS-induced membrane hyperpolarization and relaxation in the rat coronary artery. Vascular Pharmacology 53(3-4):94-98.