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圖片:林錫樂教授

林錫樂教授

副教授

教育背景

1992 理學士 香港中文大學
1996 哲學博士 香港中文大學

Position

2009年至今
香港中文大學
副教授
2003-2009
香港中文大學
助理教授
1999-2003
Assistant Professor, 
(Replacement Teacher), 
The Chinese University of Hong Kong
1997-1999
美國俄勒岡州立大學
生物化学及生物物理学系
博士後

研究興趣

  1. Biophysical chemistry of nucleic acids: (i) molecular mechanism of genetic instabilities; (ii) fidelity of DNA replication; (iii) mechanistic pathways of DNA damage and repair
  2. Development of NMR methods for structure determination of nucleic acids
  3. Application of high resolution NMR spectroscopy in biomedical analysis

Representative Publications

  1. Guo, P. and Lam, S.L. (2017). An extraordinarily stable DNA minidumbbell. J Phys Chem Lett 8, 3478-3481.
  2. Guo, P., Chan, H.Y.E. and Lam, S.L. (2017). Conformational flexibility in the RNA stem-loop structures formed by CAG repeats. FEBS Lett 591, 1752-1760.
  3. Liu, Y., Guo, P. and Lam, S.L. (2017). Formation of a DNA mini-dumbbell with a quasi-type II loop. J Phys Chem B 121, 2554-2560.
  4. Guo, P. and Lam, S.L. (2016). Unusual structures of CCTG repeats and their participation in repeat expansion. Biomol Concepts 7, 331-340.
  5. Guo, P. and Lam, S.L. (2016). Minidumbbell: a new form of native DNA structure. J Am Chem Soc 138, 12534-12540.

DSHIFT Web Server

PDF全文: Lam, S.L. (2007) DSHIFT: a web server for predicting DNA chemical shifts. Nucleic Acids Res. 35, W713-717.


榮譽和獎項

2010 王天眷波譜學獎


現有空缺

We are looking for PhD students with research background in analytical/biological/physical chemistry and will provide full financial support to the successful applicants. Applicants should apply with a resume, a transcript and a grade of English test (TOEFL) to Prof. Lam at lams@cuhk.edu.hk.