Home > People > Honorary Staff > Prof. Gigi Pui-Chi LO

 

photo of Prof. Gigi Pui-Chi LO

Prof. Gigi Pui-Chi LO

BSc, PhD
Adjunct Assistant Professor

location P6935, Academic 1,
 City University of Hong Kong
Phone No. (852) 3442 4493
Fax No. (852) 3442 0549
Email pclo@cuhk.edu.hk


Education
1998–2001 B.Sc. (Hons.) in Chemistry, First Class The Chinese University of Hong Kong
2001–2005 Ph.D. in Chemistry The Chinese University of Hong Kong

Position
Since 2015
Assistant Professor, 
Department of Biomedical Sciences, 
City University of Hong Kong, 
Since 2015
Adjunct Assistant Professor, 
Department of Chemistry, 
The Chinese University of Hong Kong, 
2009 – 2015
Research Assistant Professor, 
Department of Chemistry, 
The Chinese University of Hong Kong, 
Jan 2007 – Dec 2008
Postdoctoral Fellow, 
Division of Biophysics and Bioimaging, 
Ontario Cancer Institute, 
Canada
Sep 2005 – Jan 2007
Postdoctoral Fellow, 
Department of Chemistry, 
The Chinese University of Hong Kong 

Research Interests

  1. Development of Peptide-Conjugated Theranostic Agents for Cancer Treatment
  2. Exploration of Activatable Photosensitizers for Photodynamic Therapy (PDT) and Antimicrobial PDT.
  3. Development of Mesoporous Silica Nanoparticles as Versatile Carriers for Photosensitizers

Representative Publications

  1. “A Phthalocyanine-Peptide Conjugate with High in vitro Photodynamic Activity and Enhanced in vivo Tumour-Retention Property” 
    M.-R. Ke, S.-L. Yeung, W.-P. Fong, D. K. P. Ng* and P.-C. Lo*
    Chem. Eur. J., in press.
  2. “Photodynamic Molecular Beacons” 
    P.-C. Lo, J. F. Lovell, and G. Zheng* 
    Handbook of Biophotonics, J. Popp, V. V. Tuchin, A. Chiou and S. Heinemann (eds.), Wiley-VCH, Vol. 2, 295-304 (2011)
  3. “Unsymmetrical β-Cyclodextrins-conjugated Silicon(IV) Phthalocyanines as Highly Potent Photosensitizers for Photodynamic Therapy” 
    J. T. F. Lau, P.-C. Lo, Y.-M. Tsang, W.-P. Fong and D. K. P. Ng* 
    Chem. Commun., 47, 9657-9659 (2011).
  4. “Synthesis and in vitro Photodynamic Activities of Pegylated Distyryl Boron Dipyrromethene Derivatives” 
    H. He, P.-C. Lo,* S.-L. Yeung, W.-P. Fong and D. K. P. Ng*
    J. Med. Chem., 54, 3097-3102 (2011)
  5. “Preparation of Unsymmetrical Distyryl BODIPY Derivatives and Effects of the Styryl Substituents on their in vitro Photodynamic Properties” 
    H. He, P.-C. Lo,* S.-L. Yeung, W.-P. Fong and D. K. P. Ng*
    Chem. Commun., 47, 4748-4750 (2011)
  6. “Phthalocyanine-Polyamine Conjugates as Highly Efficient Photosensitizers for Photodynamic Therapy” 
    X.-J. Jiang, S.-L. Yeung, P.-C. Lo,* W.-P. Fong* and D. K. P. Ng* 
    J. Med. Chem., 54, 320-330 (2011)
  7. “A pH-Responsive Fluorescence Probe and Photosensitizer Based on a Tetraamino Silicon(IV) Phthalocyanine” 
    X.-J. Jiang, P.-C. Lo, S.-L. Yeung, W.-P. Fong and D. K. P. Ng* 
    Chem. Commun., 46, 3188-3190 (2010)
  8. “Photodynamic Molecular Beacon Triggered by Fibroblast Activation Protein on Cancer-Associated Fibroblasts for Diagnosis and Treatment of Epithelial Cancers” 
    P.-C. Lo, J. Chen, K. Stefflova, M. S. Warren, R. Navab, B. Bandarchi, S. Mullins, M. Tsao, J. D. Cheng and G. Zheng* 
    J. Med. Chem., 52, 358-368 (2009)
  9. “Effects of Peripheral Chloro Substitution on the Photophysical Properties and in vitro Photodynamic Activities of Galactose-Conjugated Silicon(IV) Phthalocyanines” 
    P.-C. Lo, W.-P. Fong and D. K. P. Ng* 
    ChemMedChem, 3, 1110-1117 (2008)
  10. “Highly Photocytotoxic Glucosylated Silicon(IV) Phthalocyanines. Effects of Peripheral Chloro Substitution on the Photophysical and Photodynamic Properties” 
    P.-C. Lo, C. M. H. Chan, J.-Y. Liu, W.-P. Fong and D. K. P. Ng* 
    J. Med. Chem., 50, 2100-2107 (2007)

Full List of Publications