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Research  |  Publications
Publications
1 Chan TYK.
  Ciguatera fish poisoning in East Asia and Southeast Asia. Maine Drugs 2015; 13: 3466-3478.
2 Chan TYK.
  Incidence and causes of Aconitum alkaloid poisoning in Hong Kong from 1989 to 2010. Phytotherapy Research 2015; 29: 1107-1111.
3 Chan TYK.
  Emergence and epidemiology of ciguatera in the coastal cities of southern China. Marine Drugs 2015; 13: 1175-1184.
4 Chan TYK.
  Pharmacovigilance in Hong Kong. In: Andrews EB, Moore N, editors. Mann's Pharmacovigilance. 3rd Edition, West Sussex: John Wiley & Sons, 2014: 259-261.
5 Chan TYK.
  Epidemiology and clinical features of ciguatera fish poisoning in Hong Kong. Toxins 2014; 6: 2989-2997.
6 Chan TYK.
  Aconitum alkaloid poisoning related to the culinary uses of aconite roots. Toxins 2014; 6: 2605-2611.
7 Chan TYK.
  Large outbreaks of ciguatera after consumption of brown marbled grouper.  Toxins 2014; 6: 2041-2049.
8 Chan TYK, Joynt GM.
  Prolonged profound hypotension complicating severe methyldopa overdose. International Journal of Clinical Pharmacology and Therapeutics 2014; 52: 628-630.
9 ChanTYK.
  Zopiclone induced methemoglobinemia and hemolytic anemia. International Journal of Clinical Pharmacology and Therapeutics 2014; 52: 402-406.
10 Chan TYK.
  Ciguatera caused by consumption of humphead wrasse. Toxicon 2013; 76: 255-259.
11 Chan TYK.
  Severe bradycardia and prolonged hypotension in ciguatera. Singapore Medical Journal 2013; 54: e120-e122.
12 Wong SK, Sin DWM, Kaarls R, Sargent M, Chu XG, Chan TYK, Lam CW, Seta K.
  International symposium on "Food and health: from measurement science to quality and safety". Accreditation and Quality Assurance 2012; 17: 557-560
13 Chen SPL, Ng SW, Poon WT, Lai CK, Ngan T, Tse ML, Chan TYK, Chan AWY, Mak TWL.
  Aconite poisoning over 5 years: a case series in Hong Kong and lessons towards herbal safety. Drug Safety 2012; 35: 575-587.
14 Zhang W, Chan TYK, Fan L, Guo Y, Zhou HH.
  Translating pharmacogenomics into personalized medicine and drug development. Personalized Medicine 2012; 9: 93-97.
15 Hon EKL, Leung TF, Yau HC, Chan TYK.
  Paradoxical use of oral and topical steroids in steroid-phobic patients resorting to traditional Chinese medicines. World Journal Pediatrics 2012; 8: 263-267.
16 Chan TYK.
  Vegetable-borne nitrate and nitrite and the risk of methaemoglobinaemia.  Toxicology Letters 2011; 200: 107-108.
17 Chan TYK, Chiu SW.
  Wild mushroom poisonings in Hong Kong. Southeast Asian Journal of Tropical Medicine and Public Health. 2011; 42: 468-469.
18 Chan TYK.
  Hidden aconite roots in herbal medicines. Clinical Toxicology 2010;48:92.
19 Chan TYK, Hung LK.
  Digital gangrene following a green pit viper bite. Southeast Asian Journal of Tropical Medicine and Public Health 2010; 41: 192-194.
20 Chan TYK.
  Aconite poisoning. Clinical Toxicology 2009; 47:279-285
21 Chan TYK.
  Outbreaks of severe hypoglycaemia due to illegal sexual enhancement products containing undeclared glibenclamide.  Pharmacoepidemiology and Drug Safety 2009; 18: 1250-1251.
22 Chan TYK.
  Overdose of methyldopa, indapamide and theophylline resulting in prolonged hypotension, marked diuresis and hypokalaemia in an elderly patient.
Pharmacoepidemilogy and Drug Safety 2009; 18: 977-979.
23 Chan TYK.
  Potential risks associated with the use of herbal anti-obesity products.
Drug Safety 2009; 32: 453-456.

24 Chan TYK.
  Life-threatening retroperitoneal bleeding due to warfarin-drug interactions.
Pharmacoepidemiology and Drug Safety 2009; 18: 420-422.

25 Leung H. Hung A. Hui AC. Chan TYK.
  Warfarin overdose due to the possible effects of Lycium barbarum L.
Food and Chemical Toxicology 2008; 146: 1860-1862.

26 Chan TYK.
  Preventing medication error and unintentional drug poisoning in the elderly (Editorial).
Hong Kong Medical Journal 2006; 12: 332-333.

27 Chan FWH, Wong RSM, Lau WH, Chan TYK, Cheng G, You JHS.
  Management of Chinese patients on warfarin therapy in two models of anticoagulation service – a prospective randomized trial.
British Journal of Clinical Pharmacology 2006; 62: 601-609.

28 Chan TYK.
  A probably case of amygdalin-induced peripheral neuropathy in a vegetarian with vitamin B12 deficiency.
Therapeutic Drug Monitoring 2006; 28: 140-141.
29 Wong ALN, Chan TYK.
  Interaction between warfarin and the herbal product guilinggao.
Annals of Pharmacotherapy 2003; 37: 836-838.
30 Tang EOYL, Lai CSM, Lee KKC, Wong RSM, Cheng G, Chan TYK.
  Relationship between patients' warfarin knowledge and anticoagulation control.
Annals of Pharmacotherapy 2003; 37: 34-39.
31 You JHS, Lee KKC, Chan TYK, Lau WH, Chan FKL.
  Arthritis treatment in Hong Kong – cost analysis of celecoxib versus conventional NSAIDs, with or without gastroprotective agents.
Alimentary Pharmacology and Therapeutics 2002; 16: 2089-2096.
32 Chan TYK, Kwok TCY.

 

Chronicity of neurological features in ciguatera fish poisoning.
Human and Experimental Toxicology 2001; 20: 426-428.
33 Chan TYK.
  Food-borne clenbuterol may have potential for cardiovascular effects with chronic exposure (commentary).
Journal of Toxicology Clinical Toxicology 2001; 39: 345-348.
34 Chan TYK.
  Vegetable-borne methamidophos poisoning.
Journal of Toxicology Clinical Toxicology 2001; 39: 337-338.
35 Chan TYK.
  Pyridoxine ineffective in isoniazid-induced psychosis.
Annals of Pharmacotherapy 1999; 33: 1123-1124.
36 Chan TYK.
  Health hazards due to clenbuterol residues in food.
Journal of Toxicology Clinical Toxicology 1999; 37: 517-519.
37 Chan TYK.
  Isoniazid and rifampicin rarely cause acute pancreatitis in patients with tuberculosis. International Journal of Clinical Pharmacology and Therapeutics 1999; 37: 109.
38 Chan TYK.
  Interactions of food with warfarin.
Hong Kong Practitioner 1999; 21: 11-16.
39 Chan TYK.
  Food poisoning following the consumption of clenbuterol-treated livestock.
Hong Kong Practitioner 1998; 20: 366-369.
40 Chan TYK.
  Estimates on the incidence of antidiabetic drug-induced severe hypoglycaemia in Hong Kong.
Pharmacoepidemiology and Drug Safety 1998; 7: 411-414.
41 Chan TYK.
  Lengthy persistence of ciguatoxin in the body.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1998; 92: 662.
42 Chan TYK.
  Adverse drug reaction monitoring in Hong Kong: 1986-1998.
Chinese Journal of Pharmacoepidemiology 1998; 7: 131-134.
43 Chan TYK.
  Drug interactions as a cause of overanticoagulation and bleedings in Chinese patients receiving warfarin.
International Journal of Clinical Pharmacology and Therapeutics 1998; 36: 403-405.
44 Chan TYK.
  Anti-diabetic drugs as a cause of hypoglycaemia among acute medical admissions in Hong Kong and Singapore – relationship to the prescribing patterns in diabetic patients.
Singapore Medical Journal 1998; 39: 186-188.
45 Chan TYK.
  Packaging of drugs and the risk of severe toxicity in adult self-poisonings (Editorial).
Journal of Clinical Pharmacy and Therapeutics 1997; 22: 157-158.
46 Chan TYK.
  Food delicacies as a cause of natural toxin poisonings in Hong Kong (Invited article).
Toxicology and Ecotoxicology News/Reviews 1997; 4: 124-126.
47 Chan TYK.
  Monitoring the safety of herbal medicines (Leading article).
Drug Safety 1997; 17: 209-215.
48 Yu CM, Chan TYK, Tsoi WC, Sanderson JE.
  Heparin Therapy in the Chinese – lower doses are required.
Quarterly Journal of Medicine 1997; 90: 535-543.
49 Chan TYK.
  Drug-induced syndrome of inappropriate antidiuretic hormone secretion: causes, diagnosis and management (Invited article).
Drugs and Aging 1997; 11: 27-44.

50 Chan TYK.
  Co-trimoxazole-induced severe haemolysis: the experience of a large general hospital in Hong Kong.
Pharmacoepidemiology and Drug Safety 1997; 6: 89-92.
51 Chan TYK.
  Safety packaging of acetaminophen combination preparations and severity of adult poisoning.
Journal of Toxicology Clinical Toxicology 1996; 34: 747-749.
52 Chan TYK.
  Angioedema and acute asthma attack due to the unexpected occurrence of aspirin in an over-the-counter cold preparation.
British Journal of Clinical Practice 1996; 50: 412-413.
53 Chan TYK.
  Osteomalacia during rifampicin and isoniazid therapy is rare in Hong Kong.
International Journal of Clinical Pharmacology and Therapeutics 1996; 34: 533-544.
54 Chan TYK, Chan AWK.
  Aminopyrine-induced blood dyscrasias: still a problem in many parts of the world.
Pharmacoepidemiology and Drug Safety 1996; 5: 215-219.
55 Chan TYK, Critchley JAJH, Lau JTF, Sung JJY, Chung SSC, Anderson DC.
  The relationship between upper gastrointestinal hemorrhage and drug use: a case control study.
International Journal of Clinical Pharmacology and Therapeutics 1996; 34: 304-308.
56 Chan TYK.
  Food-borne nitrates and nitrites as a cause of methemoglobinemia.
Southeast Asian Journal of Tropical Medicine and Public Health 1996; 27: 189-192.
57 Yu HCM, Chan TYK, Critchley JAJH, Woo KS.
  Factors determining the maintenance dose of warfarin in Chinese patients.
Quarterly Journal of Medicine 1996; 89: 127-135.
58 Chan TYK, Lee KKC, Chan AWK, Critchley JAJH.
  Utilization of antidiabetic drugs in Hong Kong: relation to the common occurrence of antidiabetic drug-induced hypoglycemia amongst acute medical admissions and the relative prevalence of NIDDM.
International Journal of Clinical Pharmacology and Therapeutics 1996; 34: 43-46.
59 Chan TYK.
  Shellfish-borne illnesses. A Hong Kong perspective.
Tropical and Geographical Medicine 1995; 47: 305-307.
60 Chan TYK.
  Adverse interactions between warfarin and nonsteroidal antiinflammatory drugs: mechanisms, clinical significance, and avoidance.
Annals of Pharmacotherapy 1995; 29: 1274-1283.
61 Chan TYK.
  Indapamide-induced severe hyponatremia and hypokalemia.
Annals of Pharmacotherapy 1995; 29: 1124-1128.
62 Chan TYK.
  Computer-assisted pharmacovigilance in hospitalized patients.
Annals of Pharmacotherapy 1995; 29: 788-789.
63 Chan TYK, Critchley JAJH.
  Drug-related problems as a cause of hospital admissions in Hong Kong.
Pharmacoepidemiology and Drug Safety 1995; 4: 165-170.
64 Chan TYK, Critchley JAJH.
  Reporting of adverse drug reactions in relation to general medical admissions to a teaching hospital in Hong Kong.
Pharmacoepidemiology and Drug Safety 1994; 3: 85-89.

65 Chan TYK, Chan JCN, Tomlinson B, Critchley JAJH.
  Chinese herbal medicines revisited - a Hong Kong perspective.
Lancet 1993; 342: 1532-1534.
66 Chan TYK, Critchley JAJH.
  The systems for monitoring adverse drug reactions in Hong Kong.
Pharmacoepidemiology and Drug Safety 1993; 2: 145-148.
67 Ting SM, Chan TYK, Wong WKK, Chan AYW.
  Acute methamidophos poisoning caused by contaminated green leafy vegetables.
Southeast Asian Journal of Tropical Medicine and Public Health 1993; 24: 402-403.
68 Chan TYK, Critchley JAJH, Chan JCN, Tomlinson B, Lai VSM, Anderson PJ, Lau GSN.
  The Drug and Poisons Information Bureau at the Chinese University of Hong Kong.
Journal of the Hong Kong Medical Association 1993; 45: 202-205.
69 Chan WK, Chan TYK, Luk WK, Leung VKS, Li TH, Critchley JAJH.
  A high incidence of cough in Chinese subjects treated with angiotensin converting enzyme inhibitors.
European Journal of Clinical Pharmacology 1993; 44: 299-300.
70 Chan TYK, Wang AYM.
  Life-threatening bradycardia and hypotension in a patient with ciguatera fish poisoning.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1993; 87: 71.
71 Chan TYK, Chan JCN, Critchley JAJH.
  Severe hypoglycaemia in Chinese patients with non-insulin-dependent diabetes treated with insulin or sulphonylureas.
Pharmacoepidemiology and Drug Safety 1992; 1: 207-211.
72 Chan TYK, Chan AYW, Sham J.
  The clinical features and management of ciguatera fish poisoning.
Journal of the Hong Kong Medical Association 1992; 44: 119-121.
73 Chan TYK, Chan JCN, Tomlinson B, Critchley JAJH.
  Adverse reactions to drugs as a cause of admissions to a general teaching hospital in Hong Kong.
Drug Safety 1992; 7: 235-240.
74 Chan TYK, Wang AYM, Woo J, Critchley JAJH.
  Adverse drug reactions in the elderly - the local scene.
Journal of the Hong Kong Medical Association 1991; 43: 200-204.
75 Woo J, Chan TYK.
  A high incidence of cough associated with combination therapy of hypertension with isradipine and lisinopril in Chinese subjects.
British Journal of Clinical Practice 1991; 45: 178-180.
76 Chan TYK, Critchley JAJH.
  Adverse drug reaction monitoring in Hong Kong.
Journal of the Hong Kong Medical Association 1991; 43: 150-151.
 
     
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