CUHK Huang Yu
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HUANG Yu (黃聿)

Chair Professor of Biomedical Sciences and Vascular Biology (29 September 2021-)
Head, Department of Biomedical Sciences
City University of Hong Kong

Hong Kong Research Grants Council – Senior Research Fellow
(香港研究資助局高級研究學者獎, 2020)

Fellow of the International Society for Heart Research (2019)
https://ishrworld.org/page/Fellows

Croucher Senior Research Fellow
(裘槎基金會裘槎優秀科研者獎, 2014)
https://croucher.org.hk/senior-research-fellow-yu-huang

Associate Editor, Circulation Research (American Heart Association)
https://www.ahajournals.org/res/editors

Editor, British Journal of Pharmacology (British Pharmacological Society)

Tel: 852-34427746
Fax: 852-34420549
E-mail: yu.huang@cityu.edu.hk
ORCID: 0000-0002-1277-6784
ResearcherID: K-2866-2017
Scopus ID: 57020209200
Google Scholar: Yu HUANG

______________________________________________________________

Emeritus Professor, School of Biomedical Sciences
Chinese University of Hong Kong (28 Sept 2021 -)

Adjunct Professor, School of Life Sciences, CUHK (28 Sept 2021 -)

Professor of Biomedical Sciences (1 August 2010 – 27 Sept 2021)
School of Biomedical Sciences, CUHK

Member for the Council of The Chinese University of Hong Kong (2015-2021)
香港中文大學校董會成員(校董, 2015-2021)

Fellow of The United College Assembly, CUHK (2003-)
香港中文大學聯合書院院務委員(2003-)

Director (Basic Sciences), Heart and Vascular Institute, CUHK (2007 – 2021)
香港中文大學心腦血管醫學研究所所長(2007-2021)

Professor (by courtesy), School of Life Sciences, CUHK (2009-2021)
Professor (by courtesy), The Hong Kong Institute of Diabetes and Obesity, CUHK (2014-2021)

E-mail: yu-huang@cuhk.edu.hk

 

CUHK Huang Yu
Qualifications
  • Shanghai First Medical College, CHINA (Fudan University Shanghai Medical College since 2002), Degree awarded (1983): Bachelor of Science

  • Department of Pharmacology, University of Cambridge, UK, Degree awarded (1985): Master of Philosophy

  • Department of Pharmacology, University of Cambridge, UK, Degree awarded (1988): Doctor of Philosophy

  • American Heart Association Post-doctoral Research Fellow Vermont-affiliated, 1988-1991), Department of Pharmacology, University of Vermont, USA

  • Post-doctoral Research Physiologist (1991-1993), Department of Physiology, University of California, Los Angeles, USA

Recent External Competitive Grants as Principal Investigator or Coordinator
  • Hong Kong Research Grants Council – Senior Research Fellow Scheme (GRF, 2021-2025), HK$7,798,380 (No. SRFS2021-4S04)

  • Hong Kong Research Grants Council - General Research Fund (GRF, 2021-2024): “Endothelial cell Nrf2activation inhibits atherosclerosis”. HK$1,394,799, No. 14109720
  • Health and Medical Research Fund, Hong Kong Government (2020-2023) “Selective PPARα activation directly protects vascular function through inhibition of YAP/TAZ-mediated oxidative stress and inflammation” HK$1,500,000, No. 07181286 
  • Natural Science Foundation of China, Major Research Program on Vascular Homeostasis and Remodeling (國家自然科學基金重大研究計畫項目, Jan 2020 – Dec 2021): “Hemodynamic regulation of atherogenesis: a mechanistic and intervention study on the basis of systems biology” RMB 2,400,000; No. 91939302
  • Hong Kong Research Grants Council - General Research Fund (GRF, 2020-2023): “Scavenging mitochondrial ROS by UCP2 attenuates atherosclerosis through suppression of endoplasmic reticulum stress”. HK$1,517,507, No. 14112919
  • Health and Medical Research Fund, Hong Kong Government (2019-2022) “Artificial sweeteners improve vascular function and reduce oxidative stress in diabetes and obesity” HK$1,500,000, No. 06173956
  • Hong Kong Research Grants Council - General Research Fund (GRF, 2019-2022): “Suppression of Hippo pathway mediates endothelial dysfunction through activating the BMP4-SMAD axis in metabolic disorder”. HK$868,956, No. 14109618
  • Health and Medical Research Fund, Hong Kong Government (2018-2020): “Involvement of the Hippo pathway as a novel mechanism underlying the beneficial effect of metformin against diabetic vasculopathy and insulin resistance. HK$1,200,000, No. 05161746

  • Hong Kong Research Grants Council – General Research Fund (GRF, 2018-2021): “Targeting YAP/TAZ activation to ameliorates endothelial dysfunction in diabetic miceHK$1,126,512, CUHK 14164817)

  • Health and Medical Research Fund, Hong Kong SAR Government (HMRF, 2017-2019): “Novel lipid-lowering-independent benefits of statins against vascular dysfunction in metabolic syndrome” 1,199,176 HK$, No.04153276

  • Hong Kong Research Grants Council – Collaborative Research Fund (CRF, 2017-2020): “A multi-disciplinary study on the beneficial effects of PPARD in physical exercise against diabetic vascular complications: cellular crosstalk and energy metabolism” HK$6,817,834,C4024-16W        

  • Hong Kong Research Grants Council – General Research Fund (GRF, 2017-2019): “Targeting TFEB to reverse endothelial dysfunction in diabetic mice through inhibition of autophagy” HK$1,317,102, CUHK 14124216)

  • Health and Medical Research Fund, Hong Kong SAR Government (HMRF, 2016-2018): “Molecular mechanisms of red wine resveratrol against metabolic vascular dysfunction” 1,199,696 HK$, No.13140871

  • Natural Science Foundation of China (NSFC) – National Health and Medical Science Council, Australia (NHMRC) Joint Research Scheme (2016-2020 “Identifying the epigenomic fingerprint of coronary heart disease in Chinese adults with type 2 diabetes” 3,500,000 RMB, No. 81561128017.

  • Health and Medical Research Fund, Hong Kong SAR Government (HMRF, 2015-2017): “Cellular mechanisms underlying the benefits of Danshen-derived salvianolic acid B against vascular inflammation and dysfunction in diabetes” HK$999,916, No. 12134081

  • Hong Kong Research Grants Council - General Research Fund (GRF, 2014-2017):“Critical role of Smad signaling in mediating vascular inflammation anddysfunction in diabetes and obesity” HK$959,868, CUHK14105814

  • Natural Science Foundation of China (NSFC, 2013-2016): “Cross-talk of the Toll-like receptor and bone morphogenic protein signaling and its function in metabolic vascular dysfunction” RMB 1,600,000; No. 91339117.

  • Health and Medical Research Fund, Hong Kong SAR Government (HMRF, 2013-2015): “Investigation of In Vivo and In Vitro Vascular Benefits of Vitamin D in Mouse Model of Obesity and Diabetes”' HK$993,920, No. 01122226.

  • Hong Kong Research Grants Council – Collaborative Research Fund (CRF, 2012-2015): “Physical exercise promotes vascular health: impact of mechano-transduction and novel endothelium-derived regulators” HK$7,700,000, CUHK2/CRF/12G

  • Hong Kong Research Grants Council – General Research Fund (GRF, 2012-2015): “Functional importance of PPARd and SIRT1 interaction in protecting endothelial function in diabetes and obesity” HK$1,300,000, CUHK464712

  • Hong Kong Research Grants Council – General Research Fund (GRF, 2011-2014): “Endoplasmic reticulum stress mediates endothelial dysfunction in diabetes and obesity” HK$1,000,000, CUHK465611

  • Hong Kong Research Grants Council – General Research Fund (GRF, 2010-2013): “Novel roles of uncoupling protein-2 against endothelial dysfunction and delayed endothelial regenerative repair in diabetes” HK$1,247,290, CUHK466110

  • National Science Foundation of China/Hong Kong Research Grants Council Joint Research Scheme (2009-2011): “PPARd activation prevents endothelial dysfunction in diabetes: cellular mechanisms and clinical implications” HK$534,750, N_CUHK428/09

  • Health grant related studies related to melamine incident, Hong Kong SAR Food and Health Bureau (2009-2011): “Impact of chronic tolerable daily intake of melamine and related compounds on renal and vascular function in pregnant and neonatal rats” HK$ 809,194, MI-BS-12

  • Hong Kong Research Grants Council – General Research Fund (GRF, 2008-2011): “Pivotal role of bone morphogenic protein-4 in endothelial dysfunction in diabetes” HK$1,198,369, CUHK465308

Research Interests
  • Endothelial and Metabolic Dysfunction, and Novel Biomarkers in Diabetes, Hypertension, Dyslipidemia and Estrogen Deficiency

  • Endothelium-derived Contracting Factors in the Regulation of Vascular Tone

  • Adipose Tissue Regulation of Vascular Function in Obesity, Diabetes and Hypertension

  • Ischemic Stroke and Neuronal Damage

  • Pharmacological Characterization of New Anti-diabetic and Anti-hypertensive Drugs. Hypotensive and antioxidant Actions of Biologically Active Components of Traditional Chinese Herbs and Natural Plants including Polypehnols and Ginsenosides

Academic Profile
  • 2020 Wuxi PharmaTech Life Science and Chemistry Award – The Scholar Award (2020年度藥明康德生命化學研究獎學者獎)
  • 2020-2021 Hong Kong Research Grants Council (RGC) Senior Research Fellow Award (2020 - 2021年度香港研究資助局高級研究學者獎)
  • 2019 Higher Education Outstanding Scientific Research Output Award (first-class award), The Ministry of Education, People Republic of China (2019年度高等學校科學研究优秀成果獎 - 自然科學一等獎)
  • UM Macao Distinguished Visiting Scholar, University of Macau (2019)
  • The elected Fellow of the International Society for Heart Research (ishr, 2019)

  • The 9th Asian Lecture on Vascular Biology at 8th Scientific Meeting of Asian Society for Vascular Biology, Shanghai, 3 November 2018

  • 2017 Higher Education Outstanding Scientific Research Output Award (second-class award), Ministry of Education, People Republic of China (2017年度高等學校科學研究优秀成果獎 - 自然科學二等獎, 2018)
  • Research Excellence Award 2016-2017, Chinese University of Hong Kong (香港中文大學研究卓越獎, 2017)
  • Second-class Award, The State Natural Science Award, China (中國國家自然科學獎二等獎, 2015)
  • Croucher Senior Research Fellowship Award (2014), Hong Kong Croucher Foundation (裘槎優秀科研者獎, 2014, 香港裘槎基金會)
  • The Robert F. Furchgott Lecture at the MOVD 2013 (11th International Symposium on Mechanisms of Vasodilatation), Zurich, Switzerland (4th October 2013)
  • The Office of Life Sciences Distinguished Lecture at National University of Singapore (26 April 2007)
  • First-class Award, The Natural Science Award, Chongqing Municipality Government (中國重慶市科學技術獎 - 自然科學獎一等獎, April 2013)
  • Research Excellence Award 2011-2012, Chinese University of Hong Kong (香港中文大學研究卓越獎, 2012)
  • 2011 Higher Education Outstanding Scientific Research Output Award (second-class award), Ministry of Education, People Republic of China (2011年度高等學校科學研究优秀成果獎 - 自然科學二等獎, 2012)
  • Member of the Biology and Medicine Panel, Hong Kong Research Grants Council, Hong Kong (December 2017-)

  • Member of the Grant Review Board, Health and Medical Research Fund, Food and Health Bureau, Hong Kong SAR Government (2013-)

  • Panel Member of University of Macau Multi-Year Research Grant in Engineering and Science (2013-2020)

  • Chair of the Review Panel on Biomedical Sciences, University of Macau Multi-Year Research Grant (2020-)  

  • Academic Committee Member of the Hong Kong Scholar Programme (香江學者計劃, 2011-) (http://hkscholars.org/articles/?do=list&catalog_id=1297)

  • Secretary (Internal Affair, 2011-2013), Vice-President (External Affair, 2013-) for The Society of Hong Kong Scholars (http://www.shks.org/director.asp)

  • Lecture, Visiting or Distinguished Professorship for Fudan University Shanghai Medical College (2005-); Xi’an Jiaotong University Medical Centre (2005-); Center of Medical Sciences, Guangdong Provincial People’s Hospital (2006-); Shanghai Jiaotong University Medical College (2007-); Jinan University (2008-); Peking University, School of Basic Medical Sciences (2010 -); Third Military Medical University (2010-); Shanghai TCM University affiliated Longhua Hospital (2011-); Beijing Institute of Heart, Lung & Blood Vessel Diseases (2017 -). Member of Scientific Committee, Shanghai City Vascular Biology Key Laboratory (2007-); Member of Academic Committee, Center for Obesity and Metabolic Disease at Peking University, China (2010-), Member of Academic Committee, Advanced Institute of Medical Sciences, Dalian Medical University (2015-)

  • Visiting Professorship under Academic Icon Porgramme, University of Malaya (2012 -)

  • Regular reviewer of manuscripts for 237 international journals and of abstracts for 12 international conferences

  • Regular reviewer of grant proposals for 26 granting agencies of 11 countries and regions

  • 373 invited lectures and seminars at international, regional and local conferences on vascular research

  • Elected voting member of the five-member Membership Committee, the International Union of Basic and Clinical Pharmacology (2006–10, reelected 2010-14, reelected 2014-2018) (http://www.iuphar.org/about_membership.html)

  • Corresponding member of the International Union of Basic and Clinical Pharmacology (IUPHAR) Committee on Receptor Nomenclature and Drug Classification (NC-IUPHAR) (2011-) (http://www.iuphar-db.org/nciuphar.jsp)

  • Secretary-General and the founding member of the Asian Society for Vascular Biology (2005-2010)

  • President, Asian Society for Vascular Biology (2010-2018)

  • Council Member, The Chinese Association of Pathophysiology (中國病理生理學會理事2010-2014, 2014-2018)

  • Vice-President, The Chinese Society of Vascular Medicine, Chinese Association of Pathophysiology (中國病理生理學會血管醫學專業委員會副主任委員, 2015-)

  • Vice-President, The Chinese Section, International Society of Heart Research (國際心臟研究會中國分會副主席,2016-2020-) (http://www.ishrchina.org/index.html)

  • Executive Council Member of The Chinese Section, International Society of Heart Research (國際心臟研究會中國分會常務理事,2008-2012, 2012-2016, 2016-2020) (http://www.ishrchina.org/index.html)

  • Council Member of International Society of Heart Research – Chinese Committee of Translational Medicine (國際心臟研究會中國轉化醫學工作委員會理事, 2014-2016)

  • Executive Council Member of International Society of Heart Research – Chinese Committee of Translational Medicine (國際心臟研究會中國轉化醫學工作委員會常務理事, 2016-2020)

  • Council Member, The Chinese Society of Cardiovascular Pathophysiology (中國病理生理學會心血管專業委員會理事2008-2012, 2012-2016, 2016-2020) (http://www.ishrchina.org/index.html)

  • Executive Council Member, The Chinese Society of Cardiovascular Pharmacology, Chinese Pharmacological Society (中國藥理學會心血管專業委員會常務理事, 2007-2011, 2011-2015, 2015-) (http://yxzy.hrbmu.edu.cn/cvpcn/showArt.asp?id=468)

  • Elected Council Member, The Chinese Society of Circulatory Physiology, Chinese Association for Physiological Sciences (中國生理學會循環生理專業委員會理事, 2015-2019)

  • Executive Council Member, 2nd Board of Specialty Committee of TCM Pharmacology, World Federation of Chinese Medicine Societies (世界中醫藥學會聯合會中藥藥理專業委員會常務理事Jan 2014-)

  • Hong Kong Representative at the Cardiovascular Conference across the Strait (2008-)

  • Executive Council Member (2000-2001) and Treasurer (2001-2008), Hong Kong Society of Neurosciences

  • Elected Executive Committee Member (2003-2005, 2011-2013, 2014-2016), Honorary Secretary (2006-2008), and Treasurer, Hong Kong Pharmacology Society (2009-2011)

  • Member of Public Affair Committee, The Academy of Cardiovascular Research Excellence, USA (2003-)

  • Founding Director (Basic Sciences) of the Institute of Vascular Medicine at Chinese University of Hong Kong (2007-)

  • Associate Director (External Link), School of Biomedical Sciences, CUHK (3.2020 -)

  • Associate Director (Research), School of Biomedical Sciences, CUHK (2016-2.2020)
  • Assistant Dean (Research), Faculty of Medicine, Chinese University of Hong Kong (2006-7.2013)

  • Associate Editor, Experimental Physiology (London, 2002-2003)

  • Editor, Experimental Physiology (London, 2003-2006)

  • Editor (Vascular), Clinical and Experimental Pharmacology and Physiology (Australia, 2007-2012)

  • Editor, Drug Discoveries & Therapeutics (Japan, 2008-)

  • Associate Editor, Naunyn-Schmiedeberg's Archives of Pharmacology (Europe, 2012-2019)

  • Associate Editor, Clinical and Experimental Pharmacology and Physiology (2014-2018)

  • Reviewer Editor, Frontiers in Pharmacotherapy of Inflammation (Switzerland, 2010-), Frontiers in Cardiovascular and Smooth Muscle Pharmacology (Switzerland, 2010-), Frontier in Vascular Physiology (Switzerland, 2010-) and Frontiers in Ethnopharmacology (Switzerland , 2013-)

  • Academic Editor, PLoS One (2011-, USA)

  • Co-Guest Editor for Journal of Cardiovascular Pharmacology (USA, 2014-2015)

  • Co-Guest Editor for British Journal of Pharmacology (UK, 2016-2017)
  • Editor for British Journal of Pharmacology (UK, Jan 2018- Dec 2022)
  • Associate Editor, Circulation Research (American Heart Association, USA, 2019 - 2023)

  • Member of Editorial Board or Editorial Advisory Board for SCI-indexed journals - Journal of Vascular Research (Europe (2007-2018); Cardiovascular Drug & Therapy (Europe (2011-), The Journal of Pharmacy and Pharmacology (UK, 2011-); Clinical and Experimental Pharmacology and Physiology (Australia, 2012-); Arteriosclerosis, Thrombosis and Vascular Biology (USA, 2012-); Acta Pharmacologica Sinica (China, 2012-); Scientific Reports (UK, 2014-); Cardiovascular Research (Europe, 2018-); Journal of Molecular and Cellular Cardiology (USA, 2018-)

  • Chairman, Co-Chairman or Secretariat and Member of Organizing or Scientific Committee of international and regional conferences including Satellite Symposium to the World Congress of the International Society for the Heart Research (Hong Kong, 2004), International Symposium on Mechanisms of Vasodilatation (Belgium, 2005), 11th International Symposium on Vascular Neuroeffector Mechanisms – the Official Satellite Symposium of the 15th World Congress of Pharmacology (main organizer, China, 2006), Scientific Meetings of Asian Society for Vascular Biology (China, 2005 & 2006, Singapore 2008, Hong Kong 2010, Xi’an China, 2012, Hualien Taiwan 2016), and Satellite Symposium to the World Congress of the International Society for the Heart Research and to the International Society of Hypertension (China, 2006); International Symposium on Basic Cardiology at The South China International Congress of Cardiology (China, yearly since 2006), 9th and 10th International Symposium on Resistance Arteries (ISRA, Hamilton Island, Australia, 2008; Denmark 2011); 10th International Symposium on Mechanism of Vasodilatation (MOVD 2009, Sendai, Japan 2009); The 12th International Symposium on “Vascular Neuroeffector Mechanisms” (Odense, Denmark, 24-26 June 2010); Paul M Vanhoutte Research Symposium (November 2010); Endothelium-derived Hyperpolarizing Factor (EDHF) 2012 (Paris, France, 2012);11th International Symposium on Mechanism of Vasodilatation (MOVD 2013, Zurich, Switzerland 2013); Joint Scientific Meetings of Asian Society for Vascular Biology and  the 12th International Symposium on “Vascular Neuroeffector Mechanisms” (Kuala Lumpur, Malaysia, 2014); The Symposium on “Natural Product: Neuro-Metabolic-Vascular Mechanisms” at 17th World Congress of Basic and Clinical Pharmacology (Cape Town, South Africa, 2014); 12th International Symposium on Mechanism of Vasodilatation (MOVD 2016, Mayo Clinic, Rochester, MN, USA 2016); Canada-China Symposium – ATVB 2016, Calgary, Canada 2016); 2019 World Congress of International Society for Heart Research (Beijing, China, 2019) ; 13th International Symposium on Mechanism of Vasodilatation and 7th International Symposium on Endothelium-Dependent Hyperpolarization (Rotterdam, The Netherlands, 2019); 14th International Symposium on Mechanism of Vasodilatation (Hong Kong, China, 2021); 22nd International Vascular Biology Meeting (IVBM, Oakland, CA, USA, 2022); 2022 World Congress of International Society for Heart Research, Berlin, Germany, 2022)

 

 

 

 

 

 

 

 

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