Centre for Clinical Trials on Chinese Medicine (CCTCM)

  • Director:

    Prof. LEUNG Ping Chung
  • Associate Directors:

    Prof. HON Kam Lun, Ellis
    Prof. LAM Wai Kei, Christopher
    Prof. WING Yun Kwok
  • Manager:

    Ms. FONG Yuet Shim, Carmen
  • Project Scientist:

    Dr. CHENG King Fai, William

Centre for Clinical Trials on Chinese Medicine (CCTCM) was established in 2000 at Prince of Wales Hospital , a teaching Hospital of Medical Faculty of CUHK.

The Centre is situated at 5/F, School of Public Health Building, Prince of Wales Hospital, houses the clinical and acupuncture research facilities, patient interview rooms, conference room, study area for postgraduate students as well as offices for the professional staff. A team of experts in Chinese medicine, herb formulations, acupuncture, scientific research and health care are pooled together to offer professional and logistic supports for clinical trials on Chinese medicine in the Prince of Wales Hospital as well as Partner Hospitals, Clinics and the Industry.

Our mission is to modernize Chinese medicines by conducting scientific, evidence-based clinical trials using an efficacy-driven approach.

We believe that Chinese medicine and modern medicine are complementary to each other. We focus our research on difficult areas that do not yet have effective or optimal solution in modern medicine. Around 40 clinical trial projects have completed. Some are on going.

In 2001, the project "Chinese Medicine Research and Further Development", led by the Institute of Chinese Medicine, was selected as an "Area of Excellence" by the University Grants Committee and received an award of HK$25 million to develop 5 priority projects.

Since 2000, We have established close collaborations with hospitals and clinics including Prince of Wales Hospital, Alice Ho Miu Ling Nethersole Hospital, Kwong Wah Hospital, Yan Chai Hospital, and Tuen Mun Hospital. We work closely with our partners in clinical trials, selection of herb formulations, patient selections, and academic exchanges. We held conferences and seminars jointly on occasions.

We welcome academic collaborations, with either modern or traditional streams. Joint ventures with Industries are considered on highly selective basis.

Clinical Trial Research Projects

  Completed Projects Principal Investigator (s)
/Collaborated Department (s)
01. Pilot study of Herbal Patch for Treatment of Plantar Fasciitis (2013-2014) Prof. L.K. Hung/Dr. L.F. Tse/Dr. S. Cheng
Dept. of Orthopaedics and Traumatology
02. Effects of Acupuncture for Low Back Pain during Pregnancy (2012-2013) Prof. R.C.C. Wang
Dept. of Obstetrics & Gynaecology
03. Effect of an innovative herbal supplement on oxidative stress and muscle damage after exercise in healthy males (2012-2013) Prof. S.H.S. Wong
Dept. of Sports Science and Physical Education
Prof. C.K. Wong
Dept. of Chemical Pathology
04. Effect of Modified Herbal Formula NF3 for Diabetic Foot Ulcer (2009-2012) Prof. J.C.N. Chan/Dr. R. Ozaki
Dept. of Medicine and Therapeutics
Prof. P.C. Leung
Dept. of Orthopaedics and Traumatology
05. Study of the Safety and efficacy of using acupuncture as an adjunct to optical correction for amblyopia in two children groups aged 3 to 7 and aged 7-13 (2009-2012) Prof. D.S.C. Lam/Dr. L.J. Chen
Dept. of Ophthalmology & Visual Sciences
06. Effects of Danshen & Gegen in prevention of Atherosclerosis in post-menopausal women with hypercholesterolemia (2008-2012) Prof. T.C.Y. Kwok
Dept. of Medicine and Therapeutics
07. Acupressure for Smoking Cessation in Community (2008-2010) Prof. Y.K. Wing
Dept. of Psychiatry
Prof. E.L.Y. Wong
The Jockey Club School of Public Health and Primary Care
08. Pilot Study of Effects of Chinese Herbal Medicine Gualou (fructus trichosanthis) in Treating beta-thalassaemia Intermedia Patients (2008-2010) Prof. C.K. Li / Dr. W.K. Leung
Dept. of Paediatrics
09. Effects of Acupuncture Activation of Neural Pathway on Irritable Bowel Syndrome (2008-2010) Prof. J.C.Y. Wu
Dept. of Medicine and Therapeutics
Prof. W.C.W. Chu
Dept. of Imaging and Interventional Radiology
10. Pilot Study of Effects of Acupuncture on Sleep Quality of Elderly with Dementia (2008-2010) Prof. T.C.Y. Kwok
Dept. of Medicine and Therapeutics
Jockey Club Centre Positive Ageing
11. Effects of Herbal Formula on Benign Prostatic Hyperplasia (2007-2010) Prof. C.F. Ng
Dept. of Surgery
12. Pilot Study of Effects of Herbal Formula on Prostatic Cancer (2007-2010) Prof. C.F. Ng
Dept. of Surgery
13. Effects of Herbal Formula on Post-stroke Recovery (2006-2010) Prof. L.K.S. Wong
Dept. of Medicine and Therapeutics, CUHK
Prof. T.F. Cheung
Department of Medicine, HKU
14. Effects of Herbal Formula on Sleep Disorder (2006-2010) Prof. Y.K. Wing
Dept. of Psychiatry, CUHK
Prof. K.F. Chung
Dept. of Psychiatry, HKU
15. Pilot study of Effects of Acupuncture on Depression (2006-2007) Prof. T.S. Lee
Dept. of Psychiatry
16. Cardiovascular-Protective Effects of Danshen Gegen for High Risk Hypertensive Patients (2005-2007) Prof. K.S. Woo/Dr. P. Chook
Dept. of Medicine and Therapeutics
Dr. T. Yip
Dept. of Medicine, Yan Chai Hospital
17. Effects of Herbal Formula on Cough (2005-2006) Prof. W.C.W. Wong
The Jockey Club School of Public Health and Primary Care
Dr. A.C. Lam
Dept. of Family Medicine, PWH
18. Effects of Herbal Formula on patients with Colon Cancer (2004-2007) Prof. C.T. Liew
Dept. of Anatomical &Cellular Pathology
Prof. C.W.K. Lam
Dept. of Chemical Pathology
19. Effects of Herbal Formula on patients with Lung Cancer (2004-2007) Prof. C.T. Liew
Dept. of Anatomical & Cellular Pathology
Prof. C.W.K. Lam
Dept. of Chemical Pathology
20. Effects of Herbal Formula on Prevention and Treatment of Osteoporosis (2004-2007) Prof. P.C. Leung/Dr. D. Choy
CUHK Jockey Club Centre for Osteoporosis Care and Control
21. Effects of Chinese Medicine on Alzheimer’s Disease (2004-2006) Prof. L. Baum/Prof. J. Woo
Dept. of Medicine and Therapeutics
22. Effects of Herbal Formula on Perennial Allergic Rhinitis (2004-2006) Prof. Van Hasselt/Prof. John Woo/Dr. Zhao Yu
Dept. of Otorhinolaryngology, Head & Neck Surgery
Dr. K.H. Ma
Dept. of E.N.T. Yan Chai Hospital
23. Effects of Acupuncture in Treatment of Rheumatoid Arthritis (2004-2005) Prof. E.K.M. Li/Prof. L.S. Tam
Department of Medicine and Therapeutics
24. Effects of Herbal Formula for influenza in the Elderly Population (2004) Prof. J.T.F. Lau
The Jockey Club School of Public Health and Primary Care
Prof. C.W.K. Lam/Prof. C.K. Won
Dept. of Chemical Pathology
25. Effects of Herbal Formula of Penta Herbs on Paediatric Atopic Dermatitis (Stage I/II/III) (2003-2010) Prof. E.K.L. Hon/Prof. T.F. Leung
Dept. of Paediatrics
26. Effects of Cordyceps Sinensis on Immunomodulatory Activities in Healthy Subjects (2003-2004) Prof. C.W.K. Lam/Prof. C.K. Wong
Dept. of Chemical Pathology
27. Effects of Herbal Formula on Rheumatoid Arthritis (2003-2004) Prof. E.K.M. Li/Prof. L.S. Tam
Dept. of Medicine and Therapeutics
Prof. C.W.K. Lam
Dept. of Chemical Pathology
28. Study of Immunomodulatory, Anti-tumor & Anti-aging Activities of Herbal Formula Vigconic VI-28 (2003-2004) Prof. C.W.K. Lam/Prof. C.K. Wong
Dept. of Chemical Pathology
29. Effects of Herbal Formula on prevention of Viral Infection (SARS) for Health Care Workers (2003) Prof. C.W.K. Lam/Prof. C.K. Wong
Dept. of Chemical Pathology
Prof. J.T.F. Lau
The Jockey Club School of Public Health and Primary Care
30. Effects of Danggui Buxue Tang for Menopausal Syndrome (Stage I + II) (2002-2007) Prof. C.J. Haines
Dept. of Obstetrics & Gynaecology
31. Effects of Acupuncture for control of Low Back Pain (2002-2005) Prof. P.C. Leung/Prof. K.Y. Fung/Dr. W.S. Chan
Dept. of Orthopaedics and Traumatology
32. Effects of Yunzhi & Danshen on Immunological Function in Nasopharyngeal Carcinoma Patients (2002-2005) Prof. S.F. Leung
Dept. of Clinical Oncology
Prof. C.W.K. Lam/Prof. C.K. Wong
Dept.t of Chemical Pathology
33. Effects of Acupuncture on Paediatric Enuresis (2002-2004) Prof. C.K. Yeung
Division of Paediartic Surgery, Dept. of Surgery
34. Effects of Danshen & Gegen as a Cardiac Tonic in Cardiac Patients (2002-2004) Prof. K.S. Woo/Dr. P. Chook
Dept. of Medicine and Therapeutics
35. Effects of Herbal Formula of Rehassure on Hepatitis B (2002-2004) Prof. J.J.Y. Sung/Prof. H.L.Y. Chan
Dept. of Medicine and Therapeutics
36. Effects of Yunzhi & Danshen on Immunological Function in Breast Cancer Patients (2002-2003) Prof. C.W.K. Lam/Prof. C.K. Wong
Dept. of Chemical Pathology
37. Effects of Herbal Formula for Reduction of Chemotherapy Toxicity (2001-2005) Prof. T.S.K. Mok
Dept. of Clinical Oncology
38. Effects of Herbal Formula on Children Asthma Stage I/ II/III (2001-2005) Prof. R. Sung/Prof. K.L. Cheung/Prof. T.F. Leung/Prof. A. Li
Dept. of Paediatrics
39. Effects of Herbal Formula on Bone Metastasis (2001-2004) Prof. P.C. Leung/Prof. S.M. Kumta
Dept. of Orthopaedics and Traumatology
40. Effects of Phyllanthus Compound for Hepatitis B (2001-2004) Prof. J.J.Y. Sung/Prof. H.L.Y. Chan
Dept. of Medicine and Therapeutics
41. Effects of Yunzhi & Danshen on Immunological Function in Healthy Subjects (2001-2004) Prof. C.W.K. Lam/Prof. C.K. Wong
Dept. of Chemical Pathology
42. Effects of Herbal Bath on Percutaneous Soft Tissue Healing After Strain Injury (2001-2003) Prof. L.K. Hung/Prof. P.C. Leung
Dept. of Orthopaedics and Traumatology
43. Effects of Herbal Formula for Diabetic Foot Ulcers (Limb Salvage) (2000-2008) Prof. P.C. Leung/Prof. M. Wong
Dept. of Orthopaedics and Traumatology
Dr. W.C. Wong
Kwong Wah Hospital
  On-going Projects Principal Investigator (s)
/ Collaboration Department (s)
01. Effects of Danggui Buxue Tang on Immunological function in Menopausal Women ( Commenced 2016 ) Prof. E.L.Y. Wong
School of Public Health and Primary Care
Prof. CK Wong
Department of Chemical Pathology
02. Effects of Tea Bath on Paediatrics Atopic Dermatitis ( Commenced 2016) Prof. E.K.L. Hon
Dept. of Paediatrics
03. Study on Traditional Chinese Medicine and Food Allergy ( Commenced 2016) Prof. T. Lee and Ms. J. Chan
Allergy Centre, HK Sanatorium & Hospital
Prof. E.K.L. Hon
Dept. of Paediatrics
Prof. CK Wong
Dept. of Chemical Pathology
04. Effects of Danshen Gegen on Peripheral Artery Disease ( Commenced 2015) Prof. B.P.Y. Yan
Dept. of Medicine and Therapeutics
05. Effects of Modified Herbal Formula NF3 on Chronic Non Healing Ulcers ( Commenced 2013) Prof. P.C. Leung /Dr. S Cheng
Dept. of Orthopaedics and Traumatology